Ancistrocladus Naphthylisoquinoline Alkaloids
This book describes a unique class of secondary metabolites, the mono- and dimeric-naphthylisoquinoline alkaloids. They exclusively occur in lianas of the palaeotropical Ancistrocladaceae and Dioncophyllaceae plant families. Their unprecedented structures include stereogenic centers and rotationally...
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Cham :
Springer International Publishing : Imprint: Springer,
2023.
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| Rhifyn: | 1st ed. 2023. |
| Cyfres: | Progress in the Chemistry of Organic Natural Products,
119 |
| Pynciau: | |
| Mynediad Ar-lein: | https://doi.org/10.1007/978-3-031-10457-2 |
| Tagiau: |
Ychwanegu Tag
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| LEADER | 00000nam a22000005i 4500 | ||
|---|---|---|---|
| 001 | 978-3-031-10457-2 | ||
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| 005 | 20260810171032.0 | ||
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| 020 | |a 9783031104572 |9 978-3-031-10457-2 | ||
| 024 | 7 | |a 10.1007/978-3-031-10457-2 |2 doi | |
| 050 | 4 | |a QD241-441 | |
| 072 | 7 | |a PNN |2 bicssc | |
| 072 | 7 | |a SCI013040 |2 bisacsh | |
| 072 | 7 | |a PNN |2 thema | |
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| 245 | 1 | 0 | |a Ancistrocladus Naphthylisoquinoline Alkaloids |h [electronic resource] / |c edited by A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M Dirsch. |
| 250 | |a 1st ed. 2023. | ||
| 264 | 1 | |a Cham : |b Springer International Publishing : |b Imprint: Springer, |c 2023. | |
| 300 | |a 1 online resource (XI, 335 p. 246 illus.). |b 106 illus. in color. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 490 | 1 | |a Progress in the Chemistry of Organic Natural Products, |x 2192-4309 ; |v 119 | |
| 505 | 0 | |a 1. Introduction -- 2. Naphthylisoquinoline Alkaloids, a Fascinating Class of Axially Chiral Biaryl Natural Products -- 3. Ancistrocladus, a Genus of Woody Lianas of the Monotypic Plant Family Ancistrocladaceae Widely Occurring in India, Sri Lanka, and Southeast Asia -- 4.The Indian Liana Ancistrocladus heyneanus and Ancistrocladus hamatus from Sri Lanka: Early Studies and More Recent Discoveries -- Full Absolute Stereostructures of Naphthylisoquinoline Alkaloids Directly from Crude Extracts: Characterization of New Metabolites from Ancistrocladus griffithii by the HPLC-MS/MS-NMR-ECD Triad -- 6. Ancistrobenomine A, the First Naphthylisoquinoline Alkaloid with a Hydroxymethylene Function at C-3, and Related 5,1'-Coupled Compounds -- 7. Ancistrocladus cochinchinensis from Central Vietnam, a Distinct Ancistrocladus Taxon? — Metabolite Pattern und Phylogenetic Relationship to Ancistrocladus aff. tectorius from China -- 8.Widespread Throughout Southeast Asia: Ancistrocladus tectorius, a Rich Source of Unique, Structurally Most Diverse Mono- and Dimeric Naphthylisoquinoline Alkaloids -- 9. Tables of the Naphthylisoquinoline Alkaloids and Related Compounds Isolated from Asian Ancistrocladus Species. | |
| 520 | |a This book describes a unique class of secondary metabolites, the mono- and dimeric-naphthylisoquinoline alkaloids. They exclusively occur in lianas of the palaeotropical Ancistrocladaceae and Dioncophyllaceae plant families. Their unprecedented structures include stereogenic centers and rotationally hindered, and therefore stereogenic, axes. Extended recent investigations on six Ancistrocladus species from Asia, as reported in this contribution, shed light on their fascinating phytochemical productivity, with over 100 intriguing natural products. This high chemodiversity arises from a similarly unique biosynthesis from acetate-malonate units, following a novel polyketidic pathway to plant-derived isoquinoline alkaloids. Some of the compounds show most promising anti-parasitic activities. Additionally, strategies for the regio- and stereoselective total synthesis of the alkaloids, including the directed construction of the chiral axis, are also presented. | ||
| 588 | |a Print version record. | ||
| 650 | 0 | |a Natural products. | |
| 650 | 0 | |a Biosynthesis. | |
| 650 | 0 | |a Chemistry, Organic. | |
| 650 | 0 | |a Pharmaceutical chemistry. | |
| 650 | 1 | 4 | |a Natural Products. |
| 650 | 2 | 4 | |a Biosynthesis. |
| 650 | 2 | 4 | |a Organic Chemistry. |
| 650 | 2 | 4 | |a Pharmaceutics. |
| 700 | 1 | |a Kinghorn, A. Douglas. |e editor. |0 (orcid)0000-0002-6647-8707 |1 https://orcid.org/0000-0002-6647-8707 |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 700 | 1 | |a Falk, Heinz. |e editor. |0 (orcid)0000-0001-9978-4105 |1 https://orcid.org/0000-0001-9978-4105 |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 700 | 1 | |a Gibbons, Simon. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 700 | 1 | |a Asakawa, Yoshinori. |e editor. |0 (orcid)0000-0002-1847-412X |1 https://orcid.org/0000-0002-1847-412X |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 700 | 1 | |a Liu, Ji-Kai. |e editor. |0 (orcid)0000-0001-6279-7893 |1 https://orcid.org/0000-0001-6279-7893 |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 700 | 1 | |a Dirsch, Verena M. |e editor. |0 (orcid)0000-0002-9261-5293 |1 https://orcid.org/0000-0002-9261-5293 |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9783031104565 |
| 776 | 0 | 8 | |i Printed edition: |z 9783031104589 |
| 776 | 0 | 8 | |i Printed edition: |z 9783031104596 |
| 830 | 0 | |a Progress in the Chemistry of Organic Natural Products, |x 2192-4309 ; |v 119 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-3-031-10457-2 |
| 912 | |a ZDB-2-CMS | ||
| 912 | |a ZDB-2-SXC | ||
| 950 | |a Chemistry and Materials Science (SpringerNature-11644) | ||
| 950 | |a Chemistry and Material Science (R0) (SpringerNature-43709) | ||