Retinal Degenerative Diseases XIX Mechanisms and Experimental Therapy /
This book contains the proceedings of the XIX International Symposium on Retinal Degeneration. A majority of those who spoke and presented posters at the meeting contributed to this volume. The blinding diseases of inherited retinal degenerations have no treatments, and age-related macular degenerat...
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| 其他作者: | , , , , , |
| 格式: | 電子 電子書 |
| 語言: | 英语 |
| 出版: |
Cham :
Springer International Publishing : Imprint: Springer,
2023.
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| 版: | 1st ed. 2023. |
| 叢編: | Advances in Experimental Medicine and Biology,
1415 |
| 主題: | |
| 在線閱讀: | https://doi.org/10.1007/978-3-031-27681-1 |
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書本目錄:
- High Resolution Imaging Mass Spectrometry of Human Donor Eye: Photoreceptor Cells and Basal Laminar Deposits of Age-related Macular Degeneration
- The non-canonical role of Complement Factor H in Retinal Pigment Epithelium (RPE) cells and implications for Age-related Macular Degeneration
- Macular Pigment Carotenoids and Bisretinoid A2E
- Disturbed matrix metalloproteinases activity in age-related macular degeneraton
- Current views on Chr10q26 contribuiton to age-related macular degeneration
- Untargeted lipidomic profiling of aged human retina with and without age-related macular degeneration (AMD)
- Decoding Race and Age-Relation Macular Degeneration: GPR 143 Activity is the Key
- Peroxisome proliferator-activated receptor gamma coactivator 1 alpha ( PGC-1x): a transcriptional regulator at the interface of aging and age-related macular degeneration?
- Regulation of ABCA1 by miR-33 and miR-34a in the aging eye
- The role of gene expressionregulation on genetic risk of Age-related Macular Degeneration
- Elastin layer in Bruch's membrane as a target for immunizatio or tolerization to modulate patthology in the mouse model of somke-induced ocular injury
- Repuprosing drugs for treatment of age-relation macular degeneration
- Extracellular Vesicle RNA Contents as Biomarkers for Ocular Diseases
- Proteomics of retinal extracellular vesicles: a reviw inot an unexplored mechanism in retinal health and AMD pathogenesis
- Prime Editing Strategy to Instally the PRHP2 c.828+1G A mutations
- Analysis of CRB1 Pathogenic Variants Correctable with CRISPR Base and Prime Editing
- Generation of an Avian Myeloblastosis Virus (AMV) Reverse Transcriptase Prime Editor
- Pre-existing neutralizing antibodies against different adeno-associated virus serotypes in humans and large animal models for gene therapy
- Optimization of Capillary-based Western Blotting for MYO7A
- AAV Serotypes and Their Suitability for RetinalGene Therapy
- Gene Augmentation ofautosomal dominant CRX-associated retinopathies
- Txnip gene therapy of retinitis pigmentosa improves cone health Factors affecting readthrough of natural versus premature termination codons
- Integrating Computational Approaches to Predict the Effect of Genetic Variants on Protein Stability in Retinal Degenerative Disease
- Network biology and medcine to resuce: Applications for retinal disease mechanisms and therapy
- Non-sydromic Retinal Degeneration Caused by Pathogenic Variants in Joubert Syndrome Genes
- Exonic variants that affect splicing- an opportunity for "hidden" mutations causing inherited retinal diseases
- Enhanced S-cone Syndrome, a Mini-Review
- The role of microglia in Inherited Retinal Diseases
- CD68: potential contributor to inflammation and RPE cell dystrophy
- Gene Expression of Clusterin, Tissue Inhibitor of Metalloproteinase-1, and Their receptors in Retinal Pigment Epithelial Cells and Muller Glial Cells is Modulated by Inflammatory Stresses
- Axonal Transport Defects in Retinal Ganglion Cells
- Connexins biology in the pathophysiology of retinal diseases
- Role of Nuclear NAD +in Retinal Homeostasis
- Retinal pigmented epithelium-derived ectopic norrin does not promote intraretinal angiogenesis in transgenic mice
- Caveolin-1 Muller glia exist as heat-resistant,high molecular weight complexes
- Role of VLC-PUFAs in Retinal and Macular Degeneration
- Ocular amyloid , condensates, and aggregates - higher order protein assemblies participate in both retinal degeneration and function
- Photoreceptor ion channels in signaling and disease
- The role of peripherin-2 /ROM1 complexes in photoreceptor outer segment disc morphogenesis
- Human mutations in Arl3, a small GTPase involved inlipidated cargo delibery to the cilia cause retinatl dystropthy
- Genotype-Phenotype Association in ABCA4-Associated Retinopathy
- Retinal pathoconnectomics: A Window into Neurodegeneration
- The role of Ceramide in Inherited Retinal Disease Pathology
- Extracelluar Matix: the Unexplored Aspects of Retinal Pathologies and Regeneration
- Role of TFEB in diseases assocaited with lysosomal dysfunction
- Retinoic acid receptor -related oprhan receptors (RORs) in eye development and disease
- A novel mouse model for Late-Onset Retinal Degeneration (L-ORD) devekios RPE abnormalities due to the loss of C1qtnf5/Ctrp5
- Comparison of mouse models of autosomal dominant retinitis pigmentosa due to P23H muations of Rhodopsin
- Compensatory Cone-Mediated Mechanisms in Inherited Retinal Degeneration Mouse Models: A Functional and Gene Expression Analsyis
- Inhibition of Ryanodine Receptor 1 Reduces Endoplasmic Reticulum (ER) Sress and Promotes ER Protein Degradation in Cyclic Nucleotide-gated Channel Deficiency
- Mouse choroid proteome revisited: foucs on aging
- Morphological and functional comparison of mice models for retinitis pigmentosa
- Current Advancements in Mouse Models of Retinal Disease
- Single-cell ItrnacriptomicProfiling of Muller Glia in the rd10 Retina
- Methods for in vivo characterization of proteostatis in the mouse retina
- Absence or PRCD leads to dysregulation in lipie Homeostatis resulting in disorganizationof photorecptor outer segment structure
- Expansion Microscopy of Mouse Photoreceptro Cilia
- Rod photorecptor specific ablation of Metformin target, AMPK, in preclinical model of autosomal recessvie retinitis pigmentosa
- TLR2 is highly overexpressed in retinal myeloid cells in the rd10 mouse model of retinitis pigmentosa
- Environmental light has an essentail effrect on the diseasae expression in a dominant RPE65 mutation
- Microglia Preserve Visual Function in A Mouse Model of Retinitis Pigmentosa with Rhodopsin-P23H Mutant
- Measuring the release of lactate from wild-type and rd1 mouse retina
- Aerobic glycolysis in photorecptors supports energy demand in the absence of mitochondrial coupling
- Redox Status in Retinitis Pigmentosa
- Perspectives on retinal dolichol metabolismand visual deficits in dolichol metalbolism-associated inherited disorders
- Retinal metabolic profile on IMPG2 deficiency mice with subretinal lesions
- Glutathione-coating of liposomes enhances the delivery of hydrophillic cargo to the inner nuclear layer in retinal cultures
- Modification of Mueller glial cell fate and proliferation with the use of small molecules
- A potential neuroprotective role for pyruvate kinase 2 in retinal degeneration
- Critical role of VEGF as a direct regulator of photorecptor function
- Lysine Ubiquitylation Drives Rhodopsin Protein Turnover
- In-silico prediction of MYO!C Rhodopsin Interactions and its Significance in Protein Localization and Visual Function
- A ciliary branched actin netowrk drives photoreceptor disc morphogenesis
- Revisiting the daily timing of POS phagocytosis
- Inhibition of Bacterial Peoptidoglycan Cytopahty by Retina Pigment Epithelial PGRP2 Amidase
- Understanding ischemic retinopathies: the role of Succinate and its recpto^T mutation
- Inducing neural regeneratio nfrom glia using proneural bHLH transcription factors.