Bioprocess and Analytics Development for Virus-based Advanced Therapeutics and Medicinal Products (ATMPs)
This book reviews the knowledge, methods and available techniques in the rapidly advancing field of virus based vaccines and gene therapeutics. It also highlights new innovative tools and interdisciplinary techniques for bioprocess development and analytics of viruses and viral vectors. As such, it...
Gespeichert in:
| Körperschaft: | |
|---|---|
| Weitere Verfasser: | , , |
| Format: | Elektronisch E-Book |
| Sprache: | Englisch |
| Veröffentlicht: |
Cham :
Springer International Publishing : Imprint: Springer,
2023.
|
| Ausgabe: | 1st ed. 2023. |
| Schlagworte: | |
| Online-Zugang: | https://doi.org/10.1007/978-3-031-28489-2 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
MARC
| LEADER | 00000nam a22000005i 4500 | ||
|---|---|---|---|
| 001 | 978-3-031-28489-2 | ||
| 003 | DE-He213 | ||
| 005 | 20260810160040.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 230810s2023 sz | o |||| 0|eng d | ||
| 020 | |a 9783031284892 |9 978-3-031-28489-2 | ||
| 024 | 7 | |a 10.1007/978-3-031-28489-2 |2 doi | |
| 050 | 4 | |a QR355-502 | |
| 072 | 7 | |a PSGL |2 bicssc | |
| 072 | 7 | |a SCI099000 |2 bisacsh | |
| 072 | 7 | |a PSG |2 thema | |
| 082 | 0 | 4 | |a 579.2 |2 23 |
| 082 | 0 | 4 | |a 616.96 |2 23 |
| 245 | 1 | 0 | |a Bioprocess and Analytics Development for Virus-based Advanced Therapeutics and Medicinal Products (ATMPs) |h [electronic resource] / |c edited by Saurabh Gautam, Abhilash I. Chiramel, Roland Pach. |
| 250 | |a 1st ed. 2023. | ||
| 264 | 1 | |a Cham : |b Springer International Publishing : |b Imprint: Springer, |c 2023. | |
| 300 | |a 1 online resource (XVI, 442 p. 84 illus.). |b 62 illus. in color. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 341 | 0 | |b Table of contents navigation |2 onix | |
| 341 | 0 | |b Single logical reading order |2 onix | |
| 341 | 0 | |b Short alternative textual descriptions |2 onix | |
| 341 | 0 | |b Use of color is not sole means of conveying information |2 onix | |
| 341 | 0 | |b Use of high contrast between text and background color |2 onix | |
| 341 | 0 | |b Next / Previous structural navigation |2 onix | |
| 341 | 0 | |b All non-decorative content supports reading without sight |2 onix | |
| 347 | |a text file |b PDF |2 rda | ||
| 505 | 0 | |a Chapter 1: Bioprocessing and analytical development for virus-based therapeutics -- Chapter 2: Viral Vector Upstream Processing and Clarification -- Chapter 3: Upstream processing of viral therapeutics: From host cell expansion to virus production -- Chapter 4: Leveraging virus biology and host genetic conflicts for cell line development and engineering for virus-based therapeutics -- Chapter 5: Overview of Current Downstream Processing for Modern Viral Vectors -- Chapter 6: Filtration Principles and Techniques for Bioprocessing of Viral Vector–Based Therapeutics -- Chapter 7: Chromatographic purification of viruses: State of the art and current trends -- Chapter 8: Purifying Viral Vectors - A Review of Chromatography Solutions -- Chapter 9: Particle analytics - Comparative approaches for analysis of viral vectors -- Chapter 10: Phase-Appropriate Potency Assay Development for AAV-based Gene Therapy Products -- Chapter 11: Quantification of virus infectivity – the key assay for the development ofviral therapeutics -- Chapter 12: Product-related impurities in therapeutic virus bioprocessing -- Chapter 13: Process Analytical Technologies (PAT) and Quality by Design (QbD) for bioprocessing of virus-based therapeutics -- Chapter 14: Methods and practical considerations in imaging viral therapeutics -- Chapter 15: Application of NMR Spectroscopy in Viral Assembly Characterization -- Chapter 16: Improved Production Strategies for Oncolytic Measles Viruses as a Therapeutic Cancer Treatment -- Chapter 17: Recent Advancements and Challenges in Recombinant Expression for Commercial Production of Virus Like Particles (VLPs) -- Chapter 18: Oncolytic viruses and viral gene therapy vectors: Principles of safety. | |
| 520 | |a This book reviews the knowledge, methods and available techniques in the rapidly advancing field of virus based vaccines and gene therapeutics. It also highlights new innovative tools and interdisciplinary techniques for bioprocess development and analytics of viruses and viral vectors. As such, it provides a timely and highly relevant resource, since current advances in pharmaceutical research have seen the rise of vaccines and advanced therapeutics and medicinal products (ATMPs), that rely on the power of viruses. However, developing bioprocesses and analytics required to create this often called “magic bullet” (i.e. gene therapy) remains an extremely challenging and costly task. This book offers strategies for overcoming hurdles and difficulties within in all the necessary steps of viral vector development - from scalability to purification methods and quality control. The book is intended for researchers working in academia or industry, as well as graduate students pursuing a career in virology. | ||
| 532 | 8 | |a Accessibility summary: This PDF does not fully comply with PDF/UA standards, but does feature limited screen reader support, described non-text content (images, graphs), bookmarks for easy navigation and searchable, selectable text. Users of assistive technologies may experience difficulty navigating or interpreting content in this document. We recognize the importance of accessibility, and we welcome queries about accessibility for any of our products. If you have a question or an access need, please get in touch with us at accessibilitysupport@springernature.com. | |
| 532 | 8 | |a No reading system accessibility options actively disabled | |
| 532 | 8 | |a Publisher contact for further accessibility information: accessibilitysupport@springernature.com | |
| 588 | |a Print version record. | ||
| 650 | 0 | |a Virology. | |
| 650 | 0 | |a Biomedical engineering. | |
| 650 | 0 | |a Biotechnology. | |
| 650 | 0 | |a Microbial genetics. | |
| 650 | 0 | |a Analytical biochemistry. | |
| 650 | 0 | |a Therapeutics. | |
| 650 | 1 | 4 | |a Virology. |
| 650 | 2 | 4 | |a Biomedical Engineering and Bioengineering. |
| 650 | 2 | 4 | |a Biotechnology. |
| 650 | 2 | 4 | |a Microbial Genetics. |
| 650 | 2 | 4 | |a Analytical Biochemistry. |
| 650 | 2 | 4 | |a Therapeutics. |
| 700 | 1 | |a Gautam, Saurabh. |e editor. |0 (orcid)0000-0003-0366-6169 |1 https://orcid.org/0000-0003-0366-6169 |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 700 | 1 | |a Chiramel, Abhilash I. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 700 | 1 | |a Pach, Roland. |e editor. |0 (orcid)0009-0001-2910-5848 |1 https://orcid.org/0009-0001-2910-5848 |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9783031284885 |
| 776 | 0 | 8 | |i Printed edition: |z 9783031284908 |
| 776 | 0 | 8 | |i Printed edition: |z 9783031284915 |
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-3-031-28489-2 |
| 912 | |a ZDB-2-SBL | ||
| 912 | |a ZDB-2-SXB | ||
| 950 | |a Biomedical and Life Sciences (SpringerNature-11642) | ||
| 950 | |a Biomedical and Life Sciences (R0) (SpringerNature-43708) | ||