Buchumschlag

The Medicinal Chemistry of Glucocorticoid Receptor Modulators

This book covers the design and development of glucocorticoid receptor modulators (GRM) from cortisol to antibody-drug conjugate payloads over the last 70 years. The author starts with an introduction to the background of glucocorticoid receptor modulators as potential therapeutic modalities. This i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: Hobson, Adrian (VerfasserIn)
Körperschaft: SpringerLink (Online service)
Format: Elektronisch E-Book
Sprache:Englisch
Veröffentlicht: Cham : Springer Nature Switzerland : Imprint: Springer, 2023.
Ausgabe:1st ed. 2023.
Schriftenreihe:SpringerBriefs in Molecular Science,
Schlagworte:
Medicinal chemistry.
Pharmaceutical chemistry.
Drugs > Design.
Chemistry > Data processing.
Chemistry > History.
Medicinal Chemistry.
Pharmaceutics.
Structure-Based Drug Design.
Computational Chemistry.
History of Chemistry.
Online-Zugang:https://doi.org/10.1007/978-3-031-28732-9
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Inhaltsangabe:
  • Introduction
  • cortisol-based glucocorticoids
  • metabolically inactivated glucocorticoids
  • prodrugs
  • selective glucocorticoid receptor modulators
  • polymers and particles
  • QSAR and Modelling
  • Antibody Drug Conjugates
  • Conclusion.

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