The Secret Lives of Transcription Factors In Heterochromatin Regulation /
This SpringerBrief explores unconventional functions of eight different transcription factors and concludes with a discussion of their biological significance and impact, including effects on processes within the cell nucleaus during development and in adult organisms. Chapter One details unconventi...
保存先:
| 主要な著者: | , |
|---|---|
| 団体著者: | |
| フォーマット: | 電子媒体 eBook |
| 言語: | 英語 |
| 出版事項: |
Cham :
Springer International Publishing : Imprint: Springer,
2023.
|
| 版: | 1st ed. 2023. |
| シリーズ: | SpringerBriefs in Biochemistry and Molecular Biology,
|
| 主題: | |
| オンライン･アクセス: | https://doi.org/10.1007/978-3-031-29029-9 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|
MARC
| LEADER | 00000nam a22000005i 4500 | ||
|---|---|---|---|
| 001 | 978-3-031-29029-9 | ||
| 003 | DE-He213 | ||
| 005 | 20260810160131.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 230425s2023 sz | o |||| 0|eng d | ||
| 020 | |a 9783031290299 |9 978-3-031-29029-9 | ||
| 024 | 7 | |a 10.1007/978-3-031-29029-9 |2 doi | |
| 050 | 4 | |a QH573-671 | |
| 072 | 7 | |a PSF |2 bicssc | |
| 072 | 7 | |a SCI017000 |2 bisacsh | |
| 072 | 7 | |a PSF |2 thema | |
| 082 | 0 | 4 | |a 571.6 |2 23 |
| 100 | 1 | |a Li, Willis X. |e author. |0 (orcid)0000-0001-9041-7341 |1 https://orcid.org/0000-0001-9041-7341 |4 aut |4 http://id.loc.gov/vocabulary/relators/aut | |
| 245 | 1 | 4 | |a The Secret Lives of Transcription Factors |h [electronic resource] : |b In Heterochromatin Regulation / |c by Willis X. Li, Louise Silver-Morse. |
| 250 | |a 1st ed. 2023. | ||
| 264 | 1 | |a Cham : |b Springer International Publishing : |b Imprint: Springer, |c 2023. | |
| 300 | |a 1 online resource (VI, 45 p. 6 illus.). |b 5 illus. in color. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 341 | 0 | |b Table of contents navigation |2 onix | |
| 341 | 0 | |b Single logical reading order |2 onix | |
| 341 | 0 | |b Short alternative textual descriptions |2 onix | |
| 341 | 0 | |b Use of color is not sole means of conveying information |2 onix | |
| 341 | 0 | |b Use of high contrast between text and background color |2 onix | |
| 341 | 0 | |b Next / Previous structural navigation |2 onix | |
| 341 | 0 | |b All non-decorative content supports reading without sight |2 onix | |
| 347 | |a text file |b PDF |2 rda | ||
| 490 | 1 | |a SpringerBriefs in Biochemistry and Molecular Biology, |x 2211-9361 | |
| 505 | 0 | |a Chapter 1 Introduction -- Chapter 2 Unconventional functions of transcription factors -- GAGA transcription factor -- Heterochromatin protein 1 -- Retinoblastoma protein -- STAT -- ATF-2 -- NF-kB -- Chapter 3 STAT and HP1, in their unconventional roles, promote longevity and protect against DNA damage and cancer -- STAT and HP1 promote longevity -- STAT and HP1 protect against DNA damage -- Increased levels of STAT and HP1 hinder carcinogenesis in a mouse xenograft model -- Chapter 4 The possible biological significance of transcription factors’ unconventional functions -- The epigenome -- Processes in the cell nucleus -- Future Work. | |
| 520 | |a This SpringerBrief explores unconventional functions of eight different transcription factors and concludes with a discussion of their biological significance and impact, including effects on processes within the cell nucleaus during development and in adult organisms. Chapter One details unconventional functions of the transcription factors GAGA, HP1, Rb, STAT, ATF-2 and NF-kB. Surprisingly, all of these transcription factors can be found in association with heterochromatin as well as euchromatin, and in some cases unconventional functions have been demonstrated for these heterochromatin-associated factors. Chapter Two focuses on the unconventional functions of STAT and HP1 and discusses their roles in the promotion of longevity, and in protection from cancer and DNA damage. Chapter Three explores the biological significance of the findings presented in the first two chapters and considers how global changes in the epigenome brought about by factors such as STAT and HP1 might affect processes within the cell nucleus during development and in adult organisms. This succinct yet thorough SpringerBrief is essential for researchers studying epigenetics, and to instructors of the subject. It should also appeal to people interested in the control of gene transcription and other processes in the cell nucleus, and to those interested in development. | ||
| 532 | 8 | |a Accessibility summary: This PDF does not fully comply with PDF/UA standards, but does feature limited screen reader support, described non-text content (images, graphs), bookmarks for easy navigation and searchable, selectable text. Users of assistive technologies may experience difficulty navigating or interpreting content in this document. We recognize the importance of accessibility, and we welcome queries about accessibility for any of our products. If you have a question or an access need, please get in touch with us at accessibilitysupport@springernature.com. | |
| 532 | 8 | |a No reading system accessibility options actively disabled | |
| 532 | 8 | |a Publisher contact for further accessibility information: accessibilitysupport@springernature.com | |
| 588 | |a Print version record. | ||
| 650 | 0 | |a Cytology. | |
| 650 | 0 | |a Physiology. | |
| 650 | 0 | |a Medical genetics. | |
| 650 | 1 | 4 | |a Cell Biology. |
| 650 | 2 | 4 | |a Physiology. |
| 650 | 2 | 4 | |a Medical Genetics. |
| 700 | 1 | |a Silver-Morse, Louise. |e author. |4 aut |4 http://id.loc.gov/vocabulary/relators/aut | |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9783031290275 |
| 776 | 0 | 8 | |i Printed edition: |z 9783031290282 |
| 830 | 0 | |a SpringerBriefs in Biochemistry and Molecular Biology, |x 2211-9361 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-3-031-29029-9 |
| 912 | |a ZDB-2-SBL | ||
| 912 | |a ZDB-2-SXB | ||
| 950 | |a Biomedical and Life Sciences (SpringerNature-11642) | ||
| 950 | |a Biomedical and Life Sciences (R0) (SpringerNature-43708) | ||