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Advances in Pharmacokinetics and Pharmacodynamics

This book provides a concise overview of recent advances in Pharmacokinetics (PK) and Pharmacodynamics (PD). The pharmacokinetics section covers the state of the art in Physiologically Based Pharmacokinetic (PBPK) modeling (Chapter 1) as well as the assessment of food effect on drug absorption using...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Macheras, Panos (Editor)
Format: Electronic eBook
Language:English
Published: Cham : Springer International Publishing : Imprint: Springer, 2023.
Edition:1st ed. 2023.
Series:AAPS Introductions in the Pharmaceutical Sciences, 9
Subjects:
Drug delivery systems.
Drugs > Design.
Pharmaceutical chemistry.
Metabolism.
Pharmacology.
Clinical biochemistry.
Drug Delivery.
Structure-Based Drug Design.
Pharmaceutics.
Medical Biochemistry.
Online Access:https://doi.org/10.1007/978-3-031-29541-6
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Table of Contents:
  • Pharmacokinetics
  • Chapter 1: Current status in PBPK modeling
  • Chapter 2: Physiologically based biopharmaceutics modeling (PBBM) Application on Food Effect Assessment
  • Chapter 3: Physiologically based finite time pharmacokinetic (PBFTPK) models: Inception and development
  • Chapter 4: Physiologically based finite time pharmacokinetic (PBFTPK) models: Applications
  • Pharmacodynamics
  • Chapter 5: Pharmacokinetic – Pharmacodynamic Modelling and Simulation in Clinical Practice and Studies
  • Chapter 6: On the Verge of Impossibility: Accounting for Variability Arising from Permutations of Comorbidities that Affect the Fate of Drugs in the Human Body
  • Chapter 7: Impact of Clinical Pharmacology on the Modernization of Drug Development and Regulation.

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