Kapak Resmi

Optimization-based Molecular Dynamics Studies of SARS-CoV-2 Molecular Structures Research on COVID- 19 /

COVID-19 has brought us extensive research databases in the fields of biophysics, biology, and bioinformatics. To extract valuable structural bioinformatic information of SARS-CoV-2 structural and nonstructural proteins, it is necessary to work with large-scale datasets of molecular dynamics (MD) tr...

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Detaylı Bibliyografya
Yazar: Zhang, Jiapu (Yazar)
Müşterek Yazar: SpringerLink (Online service)
Materyal Türü: Elektronik Ekitap
Dil:İngilizce
Baskı/Yayın Bilgisi: Cham : Springer Nature Switzerland : Imprint: Springer, 2023.
Edisyon:1st ed. 2023.
Seri Bilgileri:Springer Series in Biophysics, 23
Konular:
Biomolecules.
Physical biochemistry.
Macromolecules.
Molecular biology.
Biophysics.
Proteins .
Bioinformatics.
Structural Biology.
Molecular Biology.
Molecular Biophysics.
Protein Biochemistry.
Online Erişim:https://doi.org/10.1007/978-3-031-36773-1
Etiketler: Etiketle
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İçindekiler:
  • 1 Papain-Like cysteine protease (PLpro)
  • 2 3C-Like protease (3CLpro)
  • 3 RNA-dependent RNA polymerase (RdRp)
  • 4 RNA-helicase
  • 5 RNA-helicase binding with [RdRp, NSP7, NSP8a, NSP8b, pRNA, tRNA, ADP-Mg2+, ATP-Mg2+]
  • 6 RNA-helicase binding with [ADP-Mg2+, ATP-Mg2+, and RNA]
  • 7 Spike (S) glycoprotein
  • 8 Spike (S) glycoprotein D614G mutant
  • 9 Spike (S) glycoprotein N501Y mutant
  • 10 Spike (S) glycoprotein N165A-and-N234A mutant
  • 11 SARS (SARS-CoV-1)
  • 12 MERS-coronavirus (MERS)
  • 13 Human-ACE2, human-L6, human-L6R, human-nAChRs
  • 14 PLpro binding with 12 compounds
  • 15 3CLpro binding with N3/Lopinavir/Ritonavir
  • 16 3CLpro dimer binding with 7 HIV-inhibitors and Others
  • 17 Spike RBDs binding with 50 drugs
  • 18 Human ACE2 ectodomain binding with 78 drugs
  • 19 Spike-and-ACE2 binding with 100 drugs
  • 20 Envelope protein (E-protein)
  • 21 Membrane glycoprotein (M-protein)
  • 22 Nucleocapsid phosphoprotein (N-protein)
  • 23 SARS-CoV-2 RNA genome
  • 24 NSP7, NSP8, NSP9, NSP10, NSP16, NSP14
  • 25 NSP15
  • 26 Other mutants
  • 27 Vaccines and Drugs
  • 28 Pandemic Mathematical Models, Epidemiology and Virus Origins
  • A Mathematical Optimization Algorithms and Free Energy Calculations
  • References
  • Index.

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