Targeting Lysine Demethylases in Cancer and Other Human Diseases

This book provides a comprehensive summary of our current knowledge on lysine demethylases, a class of epigenetic regulators. It takes the reader on an exciting journey spanning the past two decades, starting from the initial discovery and characterization of these enzymes and leading up to the deve...

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Dades bibliogràfiques
Autor corporatiu: SpringerLink (Online service)
Altres autors: Yan, Qin (Editor)
Format: Electrònic eBook
Idioma:anglès
Publicat: Cham : Springer International Publishing : Imprint: Springer, 2023.
Edició:1st ed. 2023.
Col·lecció:Advances in Experimental Medicine and Biology, 1433
Matèries:
Accés en línia:https://doi.org/10.1007/978-3-031-38176-8
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Taula de continguts:
  • Chapter 1. Lysine demethylation in pathogenesis
  • Chapter 2. Targeting the LSD1/KDM1 Family of Lysine Demethylases in Cancer and Other Human Diseases
  • Chapter 3. KDM2 demethylases as drug targets
  • Chapter 4. Role of histone demethylase KDM3 (JMJD1) in transcriptional regulation and cancer progression
  • Chapter 5. KDM4 demethylases as drug targets
  • Chapter 6. KDM5 lysine demethylases in pathogenesis, from basic science discovery to the clinic
  • Chapter 7. Context-dependent functions of lysine demethylases in physiology and disease
  • Chapter 8. KDM7 demethylases as drug targets.