Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease
The aim of this volume is to summarize novel findings on the function, pathophysiology, and regulation of voltage-gated Ca2+ channels and on novel concepts of their pharmacological modulation. Impressive insights into the role of channel function and regulation have come from Ca2+ channelopathies af...
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| Format: | Electronic eBook |
| Language: | English |
| Published: |
Cham :
Springer International Publishing : Imprint: Springer,
2023.
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| Edition: | 1st ed. 2023. |
| Series: | Handbook of Experimental Pharmacology,
279 |
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| Online Access: | https://doi.org/10.1007/978-3-031-38437-0 |
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Table of Contents:
- Preface
- Part 1 Modulation
- Cav1.1Calcium Channel Signaling Complexes in Excitation–Contraction Coupling: Insights from Channelopathies
- Mechanisms of Vascular CaV1.2 Channel Regulation During Diabetic Hyperglycemia
- Sympathetic Nervous System Regulation of Cardiac Calcium Channels
- Modulation of CaV1.2 Channel Function by Interacting Proteins and Post-Translational Modifications: Implications in Cardiovascular Diseases and COVID-19
- Part 2 Pharmacological Approaches
- Pathophysiological Roles of Auxiliary Calcium Channel α2δ Subunits
- Design and Applications of Genetically-Encoded Voltage-Dependent Calcium Channel Inhibitors
- Part 3 Disease insight from channelopathies: consequences for pharmacology and therapeutic strategies
- CACNA1C-Related Channelopathies
- CACNA1D-Related Channelopathies: From Hypertension to Autism
- CACNA1A-Related Channelopathies: Clinical Manifestations and Treatment Options
- CaV3.2 (CACNA1H) in Primary Aldosteronism,- CaV3.3 Channelopathies
- Pathophysiological Roles of Auxiliary Calcium Channel α2δ Subunits.