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The Marathon of the Messenger A History of Messenger RNA Vaccines /

The Covid-19 pandemic changed the world. Indeed a real race took place worldwide between SARS-CoV-2 on the one hand and researchers on the other – especially those specializing in messenger RNA vaccines. Four years after its emergence, the pandemic is not over, but some decisive battles have been wo...

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Bibliografiska uppgifter
Huvudupphovsmän: Lemonnier, Jérôme (Författare, medförfattare), Lemonnier, Nicolas (Författare, medförfattare)
Institutionell upphovsman: SpringerLink (Online service)
Materialtyp: Elektronisk E-bok
Språk:engelska
Publicerad: Cham : Springer International Publishing : Imprint: Springer, 2023.
Upplaga:1st ed. 2023.
Ämnen:
Immunology.
Biology > Technique.
Biotechnology.
Molecular biology.
Industrial engineering.
Production engineering.
Biological Techniques.
Molecular Biology.
Industrial and Production Engineering.
Länkar:https://doi.org/10.1007/978-3-031-39300-6
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Innehållsförteckning:
  • Chapter 1. Introduction: The Marathon of the Messenger RNA
  • Part I. Messenger RNA, an essential role and challenge
  • Chapter 2. A short history of vaccination
  • Chapter 3. From DNA to RNA
  • Chapter 4. Messenger RNA (mRNA): from transcription to protein translation
  • Chapter 5. The mechanism of viral infection
  • Chapter 6. The immune response
  • Part II. From preliminary studies to clinical trials
  • Chapter 7. Promising studies in the 1990s
  • Chapter 8. The use of mRNA - the initial technical obstacles
  • Chapter 9. The birth of CureVac: the era of the pioneers
  • Chapter 10. Solutions for mRNA optimization
  • Chapter 11. Modified and unmodified mRNA: for what purpose?
  • Chapter 12. Experiments and clinical trials conducted: the power of therapeutic mRNA
  • Chapter 13. Experiments and clinical trials against infectious diseases
  • Chapter 14. Experiments and clinical trials against cancer
  • Chapter 15. Experiments and clinical trials carried out in other therapeutic fields
  • Chapter 16. Modified mRNA versus unmodified mRNA: not just a scientific issue
  • Part III. The triumph of messenger RNA
  • Chapter 17. A very progressive diffusion in scientific circles
  • Chapter 18. The development of future biotechs in the 2010s
  • Chapter 19. The importance of intellectual property and patents
  • Chapter 20. 2020: the triumph of anti-Covid mRNA vaccines
  • Chapter 21. mRNA, a technology of the future.

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