Macrolides as Immunomodulatory Agents

For over 50 years, clinicians have known that macrolide antibiotics have effects on inflammation and the immune system that are not related to their antimicrobial properties. These immunomodulatory properties, best described for treating inflammatory airway diseases, protect the lung and the host an...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Rubin, Bruce K. (Editor), Shinkai, Masaharu (Editor)
Format: Electronic eBook
Language:English
Published: Cham : Springer International Publishing : Imprint: Springer, 2024.
Edition:1st ed. 2024.
Series:Progress in Inflammation Research, 92
Subjects:
Online Access:https://doi.org/10.1007/978-3-031-42859-3
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505 0 |a Part I. Mechanisms of Action and Novel Macrolides -- Macrolides and Diseases Associated with Loss of Epithelial Barrier Integrity -- Macrolides and Inflammatory Cells, Signaling, and Mediators -- Part II. Clinical Use for Airway Disease -- Macrolides as Immunomodulatory Agents -- Macrolides and Cystic Fibrosis -- Non-CF Bronchiectasis -- Macrolide Use in Chronic Obstructive Pulmonary Disease -- Macrolides and Asthma Therapy -- Macrolides and Interstitial Lung Diseases -- Macrolides in Acute Respiratory Distress Syndrome and Acute Lung Injury -- Azithromycin for Other Lung Diseases: Lung Transplantation and Sarcoidosis -- Macrolides for Rhinosinusitis and Nasal Polyps -- Part III. Clinical Use for Other Diseases -- Macrolides for Cancer -- Macrolides in Chronic Skin Disorders -- Macrolide Use in Preschool Aged Children with Acute or Recurrent Respiratory Tract Illnesses with Wheezing -- Macrolides and Immunomodulation: Today and the Future. 
520 |a For over 50 years, clinicians have known that macrolide antibiotics have effects on inflammation and the immune system that are not related to their antimicrobial properties. These immunomodulatory properties, best described for treating inflammatory airway diseases, protect the lung and the host and improve clinical status. This book summarizes our current knowledge regarding proposed mechanisms for these properties, established clinical results, and what the future may hold with emphasis on novel clinical applications and the fascinating development of non-antimicrobial macrolides with preserved and enhanced immunomodulatory properties. 
532 8 |a Accessibility summary: This PDF does not fully comply with PDF/UA standards, but does feature limited screen reader support, described non-text content (images, graphs), bookmarks for easy navigation and searchable, selectable text. Users of assistive technologies may experience difficulty navigating or interpreting content in this document. We recognize the importance of accessibility, and we welcome queries about accessibility for any of our products. If you have a question or an access need, please get in touch with us at accessibilitysupport@springernature.com. 
532 8 |a No reading system accessibility options actively disabled 
532 8 |a Publisher contact for further accessibility information: accessibilitysupport@springernature.com 
588 |a Print version record. 
650 0 |a Inflammation. 
650 0 |a Cancer. 
650 0 |a Immune system. 
650 0 |a Cellular signal transduction. 
650 0 |a Immunology. 
650 0 |a Immunotherapy. 
650 1 4 |a Inflammation. 
650 2 4 |a Cancer Biology. 
650 2 4 |a Immune Cell Signalling. 
650 2 4 |a Immunology. 
650 2 4 |a Immunotherapy. 
700 1 |a Rubin, Bruce K.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
700 1 |a Shinkai, Masaharu.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
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950 |a Biomedical and Life Sciences (SpringerNature-11642) 
950 |a Biomedical and Life Sciences (R0) (SpringerNature-43708)