CNS Drug Development and Delivery Concepts and Applications /

The book covers recent advances in the field of CNS therapeutics, including opportunities posed by expanding basic knowledge related to CNS conditions and novel approaches for efficient drug delivery to the brain (e.g., pharmaceutical nanocarriers and transporter- and transcytosis-mediated drug deli...

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Bibliografiske detaljer
Institution som forfatter: SpringerLink (Online service)
Andre forfattere: Talevi, Alan (Editor)
Format: Electronisk eBog
Sprog:engelsk
Udgivet: Cham : Springer Nature Switzerland : Imprint: Springer, 2024.
Udgivelse:1st ed. 2024.
Serier:AAPS Introductions in the Pharmaceutical Sciences, 9999
Fag:
Online adgang:https://doi.org/10.1007/978-3-031-62604-3
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505 0 |a Chapter 1- Transporter-mediated drug delivery to the brain -- Chapter 2 - Mechanisms and methods for evaluating drug delivery via transcytosis to the brain -- Chapter 3 -In vitro blood-brain studies -- Chapter 4 - In silico prediction of CNS bioavailability -- Chapter 5 - Use of unbound exposure data to establish in vitro-in vivo correlations for CNS drug candidates -- Chapter 6 - Intranasal Delivery of Drugs to the Central Nervous System -- Chapter 7 - Polymeric nanoparticles for nose-to-brain delivery in Alzheimer's and Parkinson´s diseases -- Chapter 8 - Barriers of the CNS and their contribution to drug-resistant epilepsy -- Chapter 9 - Network-pharmacology and central nervous system drug development. 
520 |a The book covers recent advances in the field of CNS therapeutics, including opportunities posed by expanding basic knowledge related to CNS conditions and novel approaches for efficient drug delivery to the brain (e.g., pharmaceutical nanocarriers and transporter- and transcytosis-mediated drug delivery to the brain inhibition of the blood-brain barrier). Chapters dealing with state-of-the-art in silico and in vitro tools for predictive purposes related to CNS bioavailability are also be included. This is an ideal book for undergraduate students and graduates in the field of medicine and pharmaceutics, and professionals working in the field of brain disorders. 
532 8 |a Accessibility summary: This PDF does not fully comply with PDF/UA standards, but does feature limited screen reader support, described non-text content (images, graphs), bookmarks for easy navigation and searchable, selectable text. Users of assistive technologies may experience difficulty navigating or interpreting content in this document. We recognize the importance of accessibility, and we welcome queries about accessibility for any of our products. If you have a question or an access need, please get in touch with us at accessibilitysupport@springernature.com. 
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532 8 |a Publisher contact for further accessibility information: accessibilitysupport@springernature.com 
650 0 |a Pharmacology. 
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