CNS Drug Development and Delivery Concepts and Applications /
The book covers recent advances in the field of CNS therapeutics, including opportunities posed by expanding basic knowledge related to CNS conditions and novel approaches for efficient drug delivery to the brain (e.g., pharmaceutical nanocarriers and transporter- and transcytosis-mediated drug deli...
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| 団体著者: | |
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| その他の著者: | |
| フォーマット: | 電子媒体 eBook |
| 言語: | 英語 |
| 出版事項: |
Cham :
Springer Nature Switzerland : Imprint: Springer,
2024.
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| 版: | 1st ed. 2024. |
| シリーズ: | AAPS Introductions in the Pharmaceutical Sciences,
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| 主題: | |
| オンライン･アクセス: | https://doi.org/10.1007/978-3-031-62604-3 |
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目次:
- Chapter 1- Transporter-mediated drug delivery to the brain
- Chapter 2 - Mechanisms and methods for evaluating drug delivery via transcytosis to the brain
- Chapter 3 -In vitro blood-brain studies
- Chapter 4 - In silico prediction of CNS bioavailability
- Chapter 5 - Use of unbound exposure data to establish in vitro-in vivo correlations for CNS drug candidates
- Chapter 6 - Intranasal Delivery of Drugs to the Central Nervous System
- Chapter 7 - Polymeric nanoparticles for nose-to-brain delivery in Alzheimer's and Parkinson´s diseases
- Chapter 8 - Barriers of the CNS and their contribution to drug-resistant epilepsy
- Chapter 9 - Network-pharmacology and central nervous system drug development.