صورة الغلاف

Transcription factors in blood cell development

This book describes transcription factors in the context of hematopoietic development and reveal mechanistic insights how they orchestrate specific gene expression patterns. Several examples from lymphoid and myeloid lineages are given as well as particular examples of leukemia fusion proteins that...

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محفوظ في:
التفاصيل البيبلوغرافية
مؤلف مشترك: SpringerLink (Online service)
مؤلفون آخرون: Borggrefe, Tilman (المحرر), Giaimo, Benedetto Daniele (المحرر)
التنسيق: الكتروني كتاب الكتروني
اللغة:الإنجليزية
منشور في: Cham : Springer Nature Switzerland : Imprint: Springer, 2024.
الطبعة:1st ed. 2024.
سلاسل:Advances in Experimental Medicine and Biology, 1459
الموضوعات:
Genetic transcription.
Cytology.
Post-translational modification.
Hematopoietic system.
Developmental biology.
Gene Transcription.
Cell Biology.
Post-translational Modifications.
Haematopoietic System.
Developmental Biology and Stem Cells.
الوصول للمادة أونلاين:https://doi.org/10.1007/978-3-031-62731-6
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جدول المحتويات:
  • Part 1 – Stem/Progenitor Cells
  • Chapter 1. MYB - A Key Transcription Factor in the Hematopoietic System Subject to many Levels of Control - Roza Berhanu Lemma, Bettina Maria Fuglerud, Jon Frampton & Odd Stokke Gabrielsen
  • Part 2 – T-Cells
  • Chapter 2. Ikaros Family Transcription Factors in Lymphocyte Differentiation and Function - Philippe Kastner & Susan Chan
  • Chapter 3. The Role of the Transcriptional Co-Activator BOB.1/OBF.1 in Adaptive Immunity - Annika C. Betzler & Cornelia Brunner
  • Chapter 4. Key Functions of the Transcription Factor BCL6 during T-Cell Differentiation - Chara Konstantakopoulou & Mihalis Verykokakis
  • Part 3 – B-Cells
  • Chapter 5. The Function of E2A in B-Cell Development - Masaki Miyazaki & Kazuko Miyazaki
  • Chapter 6. Hypoxia and the Hypoxia-Inducible Factors in Lymphocyte Differentiation and Function - Mark Boothby & Sung Hoon Cho
  • Chapter 7. Early B-Cell Factor 1: An Archetype for a Lineage-Restricted Transcription Factor Linking Development to Disease - Mikael Sigvardsson
  • Part 4 – Myeloid Cells
  • Chapter 8. Transcription Factor NRF2 in Shaping Myeloid Cell Differentiation and Function - Marc Pfefferlé & Florence Vallelian
  • Part 5 – Erythroid Cells
  • Chapter 9. Trancriptional Repressor BCL11A In Erythroid Cells - Ge Zheng & Stuart H. Orkin
  • Chapter 10. Erythroid Krüppel-like Factor / KLF1: a Surprisingly Versatile Regulator of Erythroid Differentiation - James J Bieker & Sjaak Philipsen
  • Chapter 11. Transcription Factor TAL1 in Erythropoiesis - Johannes Fechner & Jörn Lausen
  • Part 6 – Megakaryocytes
  • Chapter 12. GATA1 in Normal and Pathologic Megakaryopoiesis and Platelet Development - Kaoru Takasaki & Stella T. Chou
  • Part 7 – Leukemia/Lymphoma
  • Chapter 13. The Diverse Roles of ETV6 Alterations in B-Lymphoblastic Leukemia and other Hematopoietic Cancers - Alexander C. Monovich, Aishwarya Gurumurthy & Russell J.H. Ryan
  • Chapter 14. Function of PML-RARA in Acute Promyelocytic Leukemia - Ugo Testa & Elvira Pelosi
  • Cha[ter 15. MYB as a Critical Transcription Factor and Potential Therapeutic Target in AML - Mary Louise Clarke, Odd Stokke Gabrielsen & Jon Frampton
  • Chapter 16. ETS1 Function in Leukemia and Lymphoma - Rebecca A. Luchtel
  • Chapter 17. The Molecular and Biological Function of MEF2D in Leukemia - Pengcheng Zhang & Rui Lu
  • Chapter 18. HOXA9 Regulome and Pharmacological Interventions in Leukemia - Sajesan Aryal & Rui Lu.

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