Human Challenge Studies for Vaccine Development
This volume offers insights into human challenge studies, where adult volunteers are deliberately infected with a pathogen of interest. These studies can broaden our knowledge on infections that have a rather low natural infection rate, but still bear a great threat to global health. The authors als...
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| Tác giả của công ty: | |
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| Tác giả khác: | , , , |
| Định dạng: | Điện tử eBook |
| Ngôn ngữ: | Tiếng Anh |
| Được phát hành: |
Cham :
Springer Nature Switzerland : Imprint: Springer,
2024.
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| Phiên bản: | 1st ed. 2024. |
| Loạt: | Current Topics in Microbiology and Immunology,
445 |
| Những chủ đề: | |
| Truy cập trực tuyến: | https://doi.org/10.1007/978-3-031-63118-4 |
| Các nhãn: |
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Mục lục:
- A brief history of human challenge studies (1900-2021) emphasising the virology, regulatory and ethical requirements, raison d’etre, ethnography, selection of volunteers and unit design
- Regulatory aspects of human challenge studies.-Controlled Human Infection challenge studies with RSV
- Human challenge studies with coronaviruses old and new
- Experimental urethral infection with Neisseria gonorrhoeae
- Helicobacter pylori.-Controlled human infection with Bordetella pertussis Human challenge studies for cholera
- The Controlled Human Infection Model for Enterotoxigenic Escherichia coli
- Challenges in developing a controlled human tuberculosis challenge model
- Shigella Controlled Human Infection Models: Current and Future Perspectives
- The background, role and outline approach for development of a Controlled Human Infection Model for Nontyphoidal Salmonella
- Controlled Human Malaria Infection studies in Africa - past, present, and future
- Controlled infection of humans with the hookworm parasite Necator americanus to accelerate vaccine development.