GABAB Receptor

This new edition presents an up-to-date, comprehensive overview of the GABAB receptor system, including a particular focus on the most recent therapeutic applications and potential. This receptor system has been implicated in several diseases and disorders, including gastroesophageal reflux disease,...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Байгууллагын зохиогч: SpringerLink (Online service)
Бусад зохиолчид: Colombo, Giancarlo (Засварлагч)
Формат: Цахим Цахим ном
Хэл сонгох:англи
Хэвлэсэн: Cham : Springer International Publishing : Imprint: Humana, 2024.
Хэвлэл:2nd ed. 2024.
Цуврал:The Receptors,
Нөхцлүүд:
Онлайн хандалт:https://doi.org/10.1007/978-3-031-67148-7
Шошгууд: Шошго нэмэх
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
Агуулга:
  • Section 1: Molecular Biology, Biochemistry, and Functioning of the GABAB Receptor
  • GABAB Receptor: Molecular Organization, Function, and Alternative Drug Development by Targeting Protein-Protein Interactions
  • GABAB Receptor Functioning: Focus on Allosteric Modulation
  • Section 2: Pharmacology of Baclofen
  • Historical Overview on Baclofen, the Only GABAB Receptor Agonist Approved and Available for Clinical Use
  • Baclofen for the Treatment of Spasticity and Dystonia in Cerebral Palsy
  • Baclofen for the Treatment of Cough
  • Baclofen for the Treatment of Alcohol Use Disorder
  • Baclofen Safety, Toxicity, Withdrawal, and Overdose
  • Section 3: Chemistry and Pharmacology of Positive Allosteric Modulators
  • Recent Advances on Chemistry of GABAB Receptor Allosteric Modulators
  • GABAB Receptor Positive Allosteric Modulators: Novel Approaches for Drug Design and Discovery
  • Recent Advances on GABAB Receptor Positive Allosteric Modulators as Potential Pharmacotherapies for Neuropsychiatric Disorders
  • Recent Advances on GABAB Receptor Positive Allosteric Modulators as Potential Pharmacotherapies for Substance Use Disorder and Food Addiction
  • Recent Advances on GABAB Receptor Positive Allosteric Modulators as Potential Pharmacotherapies for Alcohol Use Disorder
  • Section 4: Miscellanea
  • γ-Hydroxybutiric Acid: A GABAB/GHB Receptor Agonist with a Unique Neuropharmacological and Therapeutic Profile
  • Naturally Occurring GABAB Receptor Ligands
  • Norman G. Bowery: A Founding Father of the GABAB Receptor Research Field – Reflections on His Contribution.