Genetic Models of Down Syndrome

Down syndrome is a textbook example of a chromosomal disorder and is common, occurring in 1 in 700 live births in the US. While there are many books previously published on the genetics of Down syndrome, and many studies in diverse species, this is the first book of its kind on the research models f...

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Korporativní autor: SpringerLink (Online service)
Další autoři: Ye, Bing (Editor), Reeves, Roger (Editor)
Médium: Elektronický zdroj E-kniha
Jazyk:angličtina
Vydáno: Cham : Springer Nature Switzerland : Imprint: Springer, 2025.
Vydání:1st ed. 2025.
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On-line přístup:https://doi.org/10.1007/978-3-031-78611-2
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Obsah:
  • Chapter 1: Introduction
  • Chapter 2 : Rodent Models of Down Syndrome I: Mouse & Rat
  • Chapter 3: Rodent Models of Down Syndrome II: Mouse
  • Chapter 4: Rodent Models of Down Syndrome III: Mouse
  • Chapter 5: Modeling Down Syndrome in C. elegans
  • Chapter 6: Modeling Down Syndrome in Drosophila
  • Chapter 7: Zebrafish Models of Down Syndrome
  • Chapter 8: Using Human Brain organoids to Study Down Syndrome
  • Chapter 9: Cellular Models: Stem Cells and other Cellular Models.-Chapter 10: Conclusions and Perspectives.