Physical and Biological Barriers at the Interface Between the Gut Microbiome and the Immune System
The gut environment is fundamental to the modulation of innate and adaptive immunity, not only in the intestinal mucosa, but systemically. Immune cells constantly circulate through the intestinal tissue and gut-associated lymphoid tissue (GALT), where their phenotype and function are regulated by se...
সংরক্ষণ করুন:
| সংস্থা লেখক: | |
|---|---|
| অন্যান্য লেখক: | , |
| বিন্যাস: | বৈদ্যুতিক বৈদ্যুতিন গ্রন্থ |
| ভাষা: | ইংরেজি |
| প্রকাশিত: |
Cham :
Springer Nature Switzerland : Imprint: Springer,
2025.
|
| সংস্করন: | 1st ed. 2025. |
| মালা: | The Microbiomes of Humans, Animals, Plants, and the Environment,
5 |
| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://doi.org/10.1007/978-3-031-84065-4 |
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| 245 | 1 | 0 | |a Physical and Biological Barriers at the Interface Between the Gut Microbiome and the Immune System |h [electronic resource] / |c edited by Marika Falcone, Martina Antonini Cencicchio. |
| 250 | |a 1st ed. 2025. | ||
| 264 | 1 | |a Cham : |b Springer Nature Switzerland : |b Imprint: Springer, |c 2025. | |
| 300 | |a 1 online resource (XI, 130 p. 5 illus.). |b 4 illus. in color. | ||
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| 490 | 1 | |a The Microbiomes of Humans, Animals, Plants, and the Environment, |x 2662-6128 ; |v 5 | |
| 505 | 0 | |a 1. Intestinal Hub for development and regulation of innate and adaptive immunity -- 2. Gut microbiota and immune homeostasis at the intestinal and systemic level -- 3. The Intestinal epithelial barrier -- 4. The gut vascular barrier -- 5. Anti-microbial peptides -- 6. The mucus layer -- 7. Intestinal mucosal immunity and biological gut barriers shaping microbiota composition -- 8. Food for the immune system: dietary components for modulating systemic immunity -- 9. Microbial metabolites from commensal microbiota and immune homeostasis -- 10. Endogenous bile acid metabolites with immune regulatory functions -- 11. Neuroimmune interaction at the intestinal barrier surface -- 12. The interplay between commensal microbiota, gut barrier integrity, and mucosal immunity regulates extra-intestinal autoimmune diseases -- 13. Gut regulators of cancer -- 14. Strengthening innate and adaptive immunity against viral infections in the gut -- 15. Changing the gut environment to modulate immune response in extra-intestinal pathologies. | |
| 520 | |a The gut environment is fundamental to the modulation of innate and adaptive immunity, not only in the intestinal mucosa, but systemically. Immune cells constantly circulate through the intestinal tissue and gut-associated lymphoid tissue (GALT), where their phenotype and function are regulated by several factors, including but not limited to the commensal gut microbiota. The host-microbiome interaction, and the role of the gut microbiota in modulating innate and adaptive immunity in the intestinal mucosa and systemically, has been amply described in recent literature and reviews. This contributed volume instead explores the cutting-edge concept that gut microbiota composition is only one of the actors in intestinal immune regulation, and that several other factors -- both genetic and environmental -- modulate innate and adaptive immunity within the intestine. Each chapter in this volume addresses the various intestinal factors modulating immunity, including food components, endogenous metabolites, biological gut barrier components, and enteric neuroimmune circuits, individually and within the context of their integration with systemic components affecting immune cell phenotypes and function. In addition, it will more broadly address the role of the physical and biological barriers as key players in the interaction between immune cells and the intestinal environment, including coverage of cutting-edge in vivo technologies that have allowed the characterization of these interactions. The final chapters are dedicated to understanding how gut environment modifications are involved, and can be therapeutically manipulated in different diseases settings, including targeting the gut environment to regular response in anti-tumor immunity, fighting infections, and controlling autoimmune diseases. . | ||
| 532 | 8 | |a Accessibility summary: This PDF does not fully comply with PDF/UA standards, but does feature limited screen reader support, described non-text content (images, graphs), bookmarks for easy navigation and searchable, selectable text. Users of assistive technologies may experience difficulty navigating or interpreting content in this document. We recognize the importance of accessibility, and we welcome queries about accessibility for any of our products. If you have a question or an access need, please get in touch with us at accessibilitysupport@springernature.com. | |
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| 588 | |a Print version record. | ||
| 650 | 0 | |a Immunology. | |
| 650 | 0 | |a Medical microbiology. | |
| 650 | 0 | |a Microbial populations. | |
| 650 | 0 | |a Inflammation. | |
| 650 | 1 | 4 | |a Immunology. |
| 650 | 2 | 4 | |a Medical Microbiology. |
| 650 | 2 | 4 | |a Microbial Communities. |
| 650 | 2 | 4 | |a Inflammation. |
| 700 | 1 | |a Falcone, Marika. |e editor. |0 (orcid)0000-0001-6080-5351 |1 https://orcid.org/0000-0001-6080-5351 |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 700 | 1 | |a Antonini Cencicchio, Martina. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
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| 776 | 0 | 8 | |i Printed edition: |z 9783031935787 |
| 830 | 0 | |a The Microbiomes of Humans, Animals, Plants, and the Environment, |x 2662-6128 ; |v 5 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-3-031-84065-4 |
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