Autophagy - From Molecular Mechanisms to Flux Control in Health and Disease

This textbook describes the autophagy pathway with all its key molecular mechanisms and its physiological functions from yeast to eukaryotes in a didactic and reader-friendly manner. It provides the most critical aspects that need to be understood to foster research and clinical translation in this...

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Autor Corporativo: SpringerLink (Online service)
Outros autores: Loos, Ben (Editor), Klionsky, Daniel J. (Editor)
Formato: Electrónico eBook
Idioma:inglés
Publicado: Cham : Springer Nature Switzerland : Imprint: Springer, 2025.
Edición:1st ed. 2025.
Series:Learning Materials in Biosciences,
Subjects:
Acceso en liña:https://doi.org/10.1007/978-3-031-88121-3
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Table of Contents:
  • Chapter 1. How to Learn, and Teach, Autophagy
  • Chapter 2. Discerning autophagy pathway intermediates – transmission electron microscopy techniques
  • Chapter 3. Assessment of Autophagy: Correlative and Super-Resolution Microscopy Techniques
  • Chapter 4. Autophagy receptors couple cargo destined to be degraded with the core autophagy machinery
  • Chapter 5. The source of membrane during autophagy and the early steps in autophagosome formation
  • Chapter 6. Autophagy and neurodegenerative diseases
  • Chapter 7. Autophagy and intracellular membrane dynamics in aging and age-related diseases
  • Chapter 8. Shear stress-dependent regulation of autophagy and metabolism in kidney epithelial cells
  • Chapter 9. Autophagy assessment in diagnostic pathology: Focus on skeletal myopathies
  • Chapter 10. The role of autophagy and mitophagy in cardiomyocyte ischemic injury
  • Chapter 11. Chaperone-mediated autophagy in health and disease
  • Chapter 12. A phenotypic screening routine for the identification of autophagic flux inducers.