Receptor Tyrosine Kinases in Cancer
Receptor tyrosine kinases (RTKs) play a critical role in a variety of cellular processes including growth, differentiation, motility, and metabolism. RTKs are frequently overexpressed and their aberrant signalling is associated with various diseases including cancer. Thus, RTKs have become one of th...
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| Další autoři: | , , |
| Médium: | Elektronický zdroj E-kniha |
| Jazyk: | angličtina |
| Vydáno: |
Cham :
Springer Nature Switzerland : Imprint: Springer,
2025.
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| Vydání: | 1st ed. 2025. |
| Edice: | Cancer Drug Discovery and Development,
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| Témata: | |
| On-line přístup: | https://doi.org/10.1007/978-3-031-93894-8 |
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Obsah:
- An Introduction to Receptor Tyrosine Kinases Signal Transduction and Cancer Progression
- Tyrosine Kinases and Inflammatory Signaling in Cancer
- Molecular Mechanisms of Acquired Therapeutic Resistance to Tyrosine Kinase Targeted Therapy
- AXL and its Role in Cell Migration and Epithelial to Mesenchymal Transition
- VEGFR and its Role in Tumor Angiogenesis
- c-MET Therapeutic Target and Biomarker in Cancer
- Receptor Tyrosine Kinase signaling and Mitochondria
- Therapeutic Potential of Targeting Immune Checkpoints Along with RTKs
- Combination therapies involving RTK inhibitors
- RTKs as a Therapeutic Target by Natural Compounds in Cancer Treatment.