Quantitative Systems Pharmacology
Quantitative Systems Pharmacology as a discipline has matured over the past decade and is being used more frequently in academia and industry; however, dedicated training programs and courses are limited. This book will provide a go-to educational reference for a broad audience with topics including...
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| Format: | Elektronski eKnjiga |
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Cham :
Springer Nature Switzerland : Imprint: Springer,
2025.
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| Izdaja: | 1st ed. 2025. |
| Serija: | Handbook of Experimental Pharmacology,
289 |
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| Online dostop: | https://doi.org/10.1007/978-3-032-02692-7 |
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| 245 | 1 | 0 | |a Quantitative Systems Pharmacology |h [electronic resource] / |c edited by Erica L. Bradshaw, Mary E. Spilker. |
| 250 | |a 1st ed. 2025. | ||
| 264 | 1 | |a Cham : |b Springer Nature Switzerland : |b Imprint: Springer, |c 2025. | |
| 300 | |a 1 online resource (VIII, 354 p. 1 illus.). | ||
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| 490 | 1 | |a Handbook of Experimental Pharmacology, |x 1865-0325 ; |v 289 | |
| 505 | 0 | |a Part 1 Fundamental Modeling -- What Is QSP and Why Does It Exist A Brief History -- Breadth of Pharmacology Modeling Fundamentals of Pharmacokinetics, Pharmacodynamics, and Mechanistic Modeling -- A Framework for Quantitative Systems Pharmacology Model Execution -- Role of data in development and application of Quantitative Systems Pharmacology models -- Integrating QSP and ML to Facilitate Drug Development and Personalized Medicine -- Part 2 Model Development and Application -- Quantitative Systems Pharmacology Development and Application in Neuroscience -- Quantitative Systems Pharmacology Modeling in Immuno Oncology Hypothesis Testing, Dose Optimization, and Efficacy Prediction -- Application of Mechanistic Mathematical Modeling to Toxicology Quantitative Systems Toxicology (QST) -- The Role of Cross Institutional and Interdisciplinary Collaboration in Defining and Executing a Quantitative Systems Pharmacology Strategy -- Part 3 Current Challenges and Future Direction -- Future Directions for Quantitative Systems Pharmacology. | |
| 520 | |a Quantitative Systems Pharmacology as a discipline has matured over the past decade and is being used more frequently in academia and industry; however, dedicated training programs and courses are limited. This book will provide a go-to educational reference for a broad audience with topics including: the technology’s history, comparisons to other modeling methods and emerging opportunities to bring methods together, best practice for implementation illustrated by real-world examples, and finally a summary of where the technology is headed in the future. | ||
| 532 | 8 | |a Accessibility summary: This PDF has been created in accordance with the PDF/UA-1 standard to enhance accessibility, including screen reader support, described non-text content (images, graphs), bookmarks for easy navigation, keyboard-friendly links and forms and searchable, selectable text. We recognize the importance of accessibility, and we welcome queries about accessibility for any of our products. If you have a question or an access need, please get in touch with us at accessibilitysupport@springernature.com. Please note that a more accessible version of this eBook is available as ePub. | |
| 532 | 8 | |a No reading system accessibility options actively disabled | |
| 532 | 8 | |a Publisher contact for further accessibility information: accessibilitysupport@springernature.com | |
| 588 | |a Print version record. | ||
| 650 | 0 | |a Pharmacology. | |
| 650 | 0 | |a Bioinformatics. | |
| 650 | 0 | |a Pharmaceutical chemistry. | |
| 650 | 1 | 4 | |a Pharmacology. |
| 650 | 2 | 4 | |a Computational and Systems Biology. |
| 650 | 2 | 4 | |a Pharmaceutics. |
| 700 | 1 | |a Bradshaw, Erica L. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 700 | 1 | |a Spilker, Mary E. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
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| 950 | |a Biomedical and Life Sciences (SpringerNature-11642) | ||
| 950 | |a Biomedical and Life Sciences (R0) (SpringerNature-43708) | ||
| 950 | |a Focus Bundle Biomedical and Human Health Sciences (SpringerNature-85407) | ||