Quantitative Systems Pharmacology

Quantitative Systems Pharmacology as a discipline has matured over the past decade and is being used more frequently in academia and industry; however, dedicated training programs and courses are limited. This book will provide a go-to educational reference for a broad audience with topics including...

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Sábháilte in:
Sonraí bibleagrafaíochta
Údar corparáideach: SpringerLink (Online service)
Rannpháirtithe: Bradshaw, Erica L. (Eagarthóir), Spilker, Mary E. (Eagarthóir)
Formáid: Leictreonach Ríomhleabhar
Teanga:Béarla
Foilsithe / Cruthaithe: Cham : Springer Nature Switzerland : Imprint: Springer, 2025.
Eagrán:1st ed. 2025.
Sraith:Handbook of Experimental Pharmacology, 289
Ábhair:
Rochtain ar líne:https://doi.org/10.1007/978-3-032-02692-7
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Clár na nÁbhar:
  • Part 1 Fundamental Modeling
  • What Is QSP and Why Does It Exist A Brief History
  • Breadth of Pharmacology Modeling Fundamentals of Pharmacokinetics, Pharmacodynamics, and Mechanistic Modeling
  • A Framework for Quantitative Systems Pharmacology Model Execution
  • Role of data in development and application of Quantitative Systems Pharmacology models
  • Integrating QSP and ML to Facilitate Drug Development and Personalized Medicine
  • Part 2 Model Development and Application
  • Quantitative Systems Pharmacology Development and Application in Neuroscience
  • Quantitative Systems Pharmacology Modeling in Immuno Oncology Hypothesis Testing, Dose Optimization, and Efficacy Prediction
  • Application of Mechanistic Mathematical Modeling to Toxicology Quantitative Systems Toxicology (QST)
  • The Role of Cross Institutional and Interdisciplinary Collaboration in Defining and Executing a Quantitative Systems Pharmacology Strategy
  • Part 3 Current Challenges and Future Direction
  • Future Directions for Quantitative Systems Pharmacology.