(Macro)Molecular Crowding Life of the Pottage /
This book presents a comprehensive overview of macromolecular crowding, a fundamental biological phenomenon that arises from the high concentration of macromolecules, such as proteins, nucleic acids, and carbohydrates, within living cells. Such crowded environment significantly reduces the amount of...
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| Formato: | Recurso Electrónico livro electrónico |
| Idioma: | inglês |
| Publicado em: |
Cham :
Springer Nature Switzerland : Imprint: Springer,
2025.
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| Edição: | 1st ed. 2025. |
| Colecção: | Subcellular Biochemistry,
109 |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1007/978-3-032-03370-3 |
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Sumário:
- Chapter 1: A brief historico-philosophical overview of macromolecular crowding: Making “physiological conditions” more physiological
- Chapter 2: Effects of molecular crowding on the structural, dynamic, and functional properties of biological macromolecules: A general overview
- Chapter 3: (Macro)molecular crowding effects beyond volume exclusion
- Chapter 4: Role of aqueous media in macromolecular crowding
- Chapter 5: Effects of macromolecular crowding on the structure and dynamics of biological membranes
- Chapter 6: Effects of molecular crowding on the structure, folding, and stability of DNA
- Chapter 7: Effects of molecular crowding on the structure, folding, stability, and catalysis of RNA
- Chapter 8: Understanding the effect of macromolecular crowding on protein misfolding and aggregation
- Chapter 9: The role of macromolecular crowding in cytoskeletal organization
- Chapter 10: Macromolecular crowding in cytoplasm and cellular organelles
- Chapter 11: Macromolecular crowding in mitochondria
- Chapter 12: Molecular crowing in nuclear pore
- Chapter 13: Catalytic Droplets: Enzyme Containing Microcompartments
- Chapter 14: Macromolecular crowding in cell stress and death
- Chapter 15: Heterogeneity of molecular crowding and liquid-liquid phase separation
- Chapter 16: Reshuffling overcrowded milieu: Stress-induced reorganization of the eukaryotic membrane-less organelles
- Chapter 17: Crowding in Anhydrobiosis
- Chapter 18: Crowding and in-cell crystallization
- Chapter 19: Macromolecular crowding for reparative medicine and drug discovery applications
- Chapter 20: Simulating crowding in vitro: Not an elusive goal any longer
- Chapter 21: Molecular Crowding by Computational Approaches
- Chapter 22: Modeling Facilitated Diffusion of Proteins in Crowded Environment
- Chapter 23: The Hidden Influences of Macromolecular Crowding: A New Frontier in Cellular Biology and Medicine.