The Calabar Bean and its Alkaloids From Magic, via Miracle, to Memory /
Investigations into Calabar beans (the dried ripe seeds of Physostigma venenosum) and their alkaloidal components compose a classical scientific journey throughout some one-and-a-half centuries and not only represent a fascinating aspect of the history of medicine but which is, moreover, still ongoi...
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| Materialtyp: | Elektronisk E-bok |
| Språk: | engelska |
| Publicerad: |
Dordrecht :
Springer Netherlands : Imprint: Springer,
2023.
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| Upplaga: | 1st ed. 2023. |
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| Länkar: | https://doi.org/10.1007/978-94-024-1191-1 |
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| 001 | 978-94-024-1191-1 | ||
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| 020 | |a 9789402411911 |9 978-94-024-1191-1 | ||
| 024 | 7 | |a 10.1007/978-94-024-1191-1 |2 doi | |
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| 072 | 7 | |a PSB |2 thema | |
| 082 | 0 | 4 | |a 572.2 |2 23 |
| 100 | 1 | |a Robinson, Brian. |e author. |4 aut |4 http://id.loc.gov/vocabulary/relators/aut | |
| 245 | 1 | 4 | |a The Calabar Bean and its Alkaloids |h [electronic resource] : |b From Magic, via Miracle, to Memory / |c by Brian Robinson. |
| 250 | |a 1st ed. 2023. | ||
| 264 | 1 | |a Dordrecht : |b Springer Netherlands : |b Imprint: Springer, |c 2023. | |
| 300 | |a 1 online resource (XXVI, 267 p. 240 illus.). | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 505 | 0 | |a Chronology -- Abbreviations -- Preface and acknowledgements -- 1. Introduction -- 2. l-Physostigmine (eserine) -- 3. l-Physovenine -- 4. l-Eseramine -- 5. l-N(8)-Norphysostigmine -- 6. l-Geneserine -- 7. 1H-, 13C- and 15N-Nuclear magnetic resonance spectra of the alkaloids of the Calabar bean -- 8. Other alkaloids of, as yet, unknown structures that have been isolated, or allegedly so, from the Calabar bean -- 9. Non-alkaloidal components of the Calabar bean -- 10. Biological activities of the alkaloids of the Calabar bean -- 11. Notes -- 12. References -- 13. Index. | |
| 520 | |a Investigations into Calabar beans (the dried ripe seeds of Physostigma venenosum) and their alkaloidal components compose a classical scientific journey throughout some one-and-a-half centuries and not only represent a fascinating aspect of the history of medicine but which is, moreover, still ongoing at the forefront of chemical and medical discovery. Those in particular involving its major such component, l-physostigmine, have led to an understanding of some of the fundamental mechanisms occurring in physiology, pharmacology and biochemistry and, either actually or potentially (by providing a template and thereby acting as a “lead compound”) have provided a useful treatment for a variety of neurological disorders associated with irregularities in cholinergic transmission in which augmentation of cholinergic activity has proved to be beneficial. | ||
| 588 | |a Print version record. | ||
| 650 | 0 | |a Botanical chemistry. | |
| 650 | 0 | |a Chemistry, Organic. | |
| 650 | 0 | |a Pharmaceutical chemistry. | |
| 650 | 1 | 4 | |a Plant Biochemistry. |
| 650 | 2 | 4 | |a Organic Chemistry. |
| 650 | 2 | 4 | |a Pharmaceutics. |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9789402411904 |
| 776 | 0 | 8 | |i Printed edition: |z 9789402411928 |
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-94-024-1191-1 |
| 912 | |a ZDB-2-SBL | ||
| 912 | |a ZDB-2-SXB | ||
| 950 | |a Biomedical and Life Sciences (SpringerNature-11642) | ||
| 950 | |a Biomedical and Life Sciences (R0) (SpringerNature-43708) | ||