Antibody-Drug Conjugates and Cellular Metabolic Dynamics

This book summarizes the related research achievements in Antibody-drug conjugates (ADCs) and their cell metabolism kinetics. The book has three main parts. The first part describes the basic theory of ADCs, including the basic concept and structure of ADCs, and the relationship between the targets...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
مؤلف مشترك: SpringerLink (Online service)
مؤلفون آخرون: Chen, Shuqing (المحرر), Zhan, Jinbiao (المحرر)
التنسيق: الكتروني كتاب الكتروني
اللغة:الإنجليزية
منشور في: Singapore : Springer Nature Singapore : Imprint: Springer, 2023.
الطبعة:1st ed. 2023.
الموضوعات:
الوصول للمادة أونلاين:https://doi.org/10.1007/978-981-19-5638-6
الوسوم: إضافة وسم
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جدول المحتويات:
  • Antibody-Drug Conjugates Basic Concepts and Structures
  • Relationship between target and specific action of antibody-drugs conjugates
  • The internalization and therapeutic activity of antibody drug conjugate
  • The internalization and intracellular trafficking of ADC
  • Distribution and metabolism of antibody-drug conjugates
  • Application of Antibody fragments in ADCs
  • Novel Targeting Carriers in Antibody-drug Conjugates
  • Site-specified Conjugating Technology and Application
  • Determination of drug-to-antibody ratio of ADCs
  • Pharmacokinetic study of antibody-drug conjugates.