Drugs and a Methodological Compendium From bench to bedside /

This book provides a meticulous view on methodological drug discovery and development insights from bench to bedside. The current book threads almost each step encompassing drug the discovery and development of a molecule. The chapters focus on computational modus operandi, pharmacological optimizat...

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Opis bibliograficzny
Korporacja: SpringerLink (Online service)
Kolejni autorzy: Rajput, Vikrant Singh (Redaktor), Runthala, Ashish (Redaktor)
Format: Elektroniczne E-book
Język:angielski
Wydane: Singapore : Springer Nature Singapore : Imprint: Springer, 2023.
Wydanie:1st ed. 2023.
Hasła przedmiotowe:
Dostęp online:https://doi.org/10.1007/978-981-19-7952-1
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Spis treści:
  • Chapter 1.Computational and informatics methodologies in Drug Discovery, with focus on Natural Products
  • Chapter 2.Structural biology an essential tool for Drug discovery and Development
  • Chapter 3.Bioactivity guided fractionation and identification of bioactive molecules: A basic method in drug discovery
  • Chapter 4.In–vitro methodologies for the safety assessment of drugs
  • Chapter 5.In-vivo models for evaluation of Drug efficacy: Demand and Challenges
  • Chapter 6.Preclinical In vivo Drug Development Studies: Limitations, Model Organisms and Techniques
  • Chapter 7.Peptide Based Therapeutics and Drug Delivery Systems
  • Chapter 8.Basics of Clinical Drug Development: Clinical Trial and Drug Development
  • Chapter 9.Trailblazing contemporary frameworks for drug repurposing: A saga on drugs’ expedition to disinter the veiled destiny
  • Chapter 10.Small molecules as promising tool for targeted cancer therapies: an overview of 21st century
  • Chapter 11.Nanoparticles for Targeted DrugDelivery Systems with Cancer Therapy in Perspective
  • Chapter 12.Biomimetic approach for the controlled drug delivery through 3D bioactive scaffolds: A novel strategy for tissue engineering applications
  • Chapter 13.Perspectives on anti-tuberculosis drug discovery
  • Chapter 14.Cofactor-Receptor interactions based pharmacophore design for development of novel inhibitors: A case study against Tuberculosis
  • Chapter 15.Insilico identification of potential antivirals against SARS-CoV2 main protease and RBD of spike protein – A Drug Repurposing Approach
  • Chapter16.Anti-malarial drug discovery and development: from bench to bedside.