Mechanobiology of Hydrostatic Pressure Frontiers of Biomechanics /

This book compiles and reorganizes previously published research to give readers a clear overview of how living systems respond to hydrostatic pressure—a force present from the deepest oceans to the human body. Although scientists have recognized its importance for decades, many questions remain. By...

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Bibliografske podrobnosti
Glavni avtor: Nagatomi, Jiro (Author)
Korporativna značnica: SpringerLink (Online service)
Format: Elektronski eKnjiga
Jezik:angleščina
Izdano: Singapore : Springer Nature Singapore : Imprint: Springer, 2025.
Izdaja:1st ed. 2025.
Serija:Frontiers of Biomechanics, 5
Teme:
Online dostop:https://doi.org/10.1007/978-981-95-4405-9
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Kazalo:
  • Part 1. What is hydrostatic pressure and why is it important for Biomechanics
  • Chapter 1.Physics of hydrostatic pressure, continuum mechanics (hydrostatic stress) vs. fluid mechanics (HP as a thermodynamic quantity)
  • Chapter 2. Hydrostatic pressure in nature (plant, deep sea biology, bacteria/microorganism)
  • Chapter 3. Hydrostatic pressure in mammalian physiology and pathology, various organ systems
  • Part 2. In vitro studies of HP mechanobiology
  • Chapter 4. HP vs stretch (Bladder, lungs, vascular)
  • Chapter 5. HP vs flow (Vascular, Bone)
  • Chapter 6. HP vs osmotic (cancer, brain, kidney),- Chapter 7. Static vs dynamic HP (Chondrocyte, IVD)
  • Chapter 8. In vitro systems criticism (ocular)
  • Part 3. Events and pathways involved in HP Mechanotransduction.-Chapter 9. Intracellular signal transduction
  • Chapter 10. Cell volume regulation, aquaporin, membrane, cytoskeleton
  • Chapter 11. Membrane bound ion channels and calcium signaling
  • Chapter 12. ATP release, purinergic signaling, DAMP, inflammasome
  • Chapter 13. ECM synthesis, fibrosis, EMT
  • Conclusion.