Development of Mirror-Image VHHs with Less Immunogenicity

This book outlines the chemical synthesis of therapeutic targets and a screening process for unexplored mirror-image single-domain antibodies (D-VHH). This book first describes the chemical synthesis of model VHH and the characteristics of both enantiomeric VHHs, including binding activity, biodistr...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолч: Aoki, Keisuke (Зохиогч)
Байгууллагын зохиогч: SpringerLink (Online service)
Формат: Цахим Цахим ном
Хэл сонгох:англи
Хэвлэсэн: Singapore : Springer Nature Singapore : Imprint: Springer, 2025.
Хэвлэл:1st ed. 2025.
Цуврал:Springer Theses, Recognizing Outstanding Ph.D. Research,
Нөхцлүүд:
Онлайн хандалт:https://doi.org/10.1007/978-981-96-1301-4
Шошгууд: Шошго нэмэх
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
Агуулга:
  • Chapter 1.Introduction
  • Chapter 2.Chemical Synthesis of Mirror-Image VHHs and Evaluation of Their Immunogenicity
  • Chapter 3.Identification of a Mirror-Image VHH against Vascular Endothelial Growth Factor
  • Chapter 4.Synthetic Study of Full-Length Hepatitis B Virus Core Protein and Its Capsid Assembly
  • Chapter 5.Chemical Synthesis of Interleukin-6 for Mirror-Image VHH Discovery
  • Chapter 6.Conclusions.