Proteostasis Investigating Molecular Dynamics in Neurodegenerative Disorders /

This book explores the role of proteostasis in neurodegenerative disorders, focusing on protein homeostasis in long-lived, nondividing cells like neurons. It examines how disruptions in proteostasis, influenced by factors such as oxidative stress, aging, and environmental stress, contribute to disea...

詳細記述

保存先:
書誌詳細
団体著者: SpringerLink (Online service)
その他の著者: Puranik, Nidhi (編集者)
フォーマット: 電子媒体 eBook
言語:英語
出版事項: Singapore : Springer Nature Singapore : Imprint: Springer, 2025.
版:1st ed. 2025.
主題:
オンライン・アクセス:https://doi.org/10.1007/978-981-96-6202-9
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目次:
  • 1. Neurodegenerative disorder: An overview
  • 2. Alzheimer's: Epidemiology, pathophysiology, diagnosis and treatments
  • 3. Parkinson’s Disease: Epidemiology, Pathophysiology, Diagnosis, and Treatment
  • 4. A Proteasome System and Impairment in Ubiquitin-Proteasome System in Neurodegeneration and Neuroprotection
  • 5. Protein misfolding and cell death in neurodegenerative diseases: consequences and strategies
  • 6. Proteostasis disturbances and inflammation in neurodegenerative diseases
  • 7. Proteostasis: Investigating Molecular Dynamics in Neurodegenerative Disorders
  • 8. Biomarkers for Proteostasis Disruption: An Overview
  • 9. Insights into Proteostasis System in Ageing and Neurodegenerative Disorders
  • 10. The role of chaperones and cochaperones in synaptic proteostasis and neurodegenerative disease
  • 11. Proteasomal Degradation and Autophagy in Neurodegenerative Diseases
  • 12. The Insight into the Role of Protein Misfolding and Tau Oligomers in Alzheimer's Disease
  • 13. Therapeutic Strategies Targeting Amyloid-β in Alzheimer’s Disease
  • 14. A comprehensive review of the ubiquitin-proteasome system in synapse remodeling and neurodegenerative diseases
  • 15. Endoplasmic Reticulum Stress and Protein Misfolding in Neurodegenerative Diseases
  • 16. Ameliorative Effects of Heat Shock Proteins in Therapeutic Implications of Neurodegenerative Diseases
  • 17. Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies
  • 18. Future Perspectives and Challenges in the Field of Proteostasis and Neurodegenerative Disorders.