Advances and Prospects of 3-d Metal-Based Anticancer Drug Candidates
This book reviews the potential of metallodrugs against different cancer. It summarizes the classification of metal-based anti-cancer drugs, their plausible biochemical and mechanistic pathways, combining drug strategies for hitting multiple therapeutic targets at the intracellular level, and advanc...
সংরক্ষণ করুন:
| প্রধান লেখক: | , , |
|---|---|
| সংস্থা লেখক: | |
| বিন্যাস: | বৈদ্যুতিক বৈদ্যুতিন গ্রন্থ |
| ভাষা: | ইংরেজি |
| প্রকাশিত: |
Singapore :
Springer Nature Singapore : Imprint: Springer,
2024.
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| সংস্করন: | 1st ed. 2024. |
| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://doi.org/10.1007/978-981-97-0146-9 |
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| 100 | 1 | |a Arjmand, Farukh. |e author. |4 aut |4 http://id.loc.gov/vocabulary/relators/aut | |
| 245 | 1 | 0 | |a Advances and Prospects of 3-d Metal-Based Anticancer Drug Candidates |h [electronic resource] / |c by Farukh Arjmand, Sartaj Tabassum, Huzaifa Yasir Khan. |
| 250 | |a 1st ed. 2024. | ||
| 264 | 1 | |a Singapore : |b Springer Nature Singapore : |b Imprint: Springer, |c 2024. | |
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| 505 | 0 | |a 1. Introduction -- 2. Classification of Metal-Based Anticancer Chemotherapeutic Agents -- 3. Interaction Studies of Metal-Based Anticancer Drug Entities with Potential Therapeutic Targets -- 4. Biophysical and Spectroscopic Techniques to Validate the Interaction with Therapeutic targets -- 5. DNA Condensation Processes mediated by Metal-based Drug Entities and Morphological Studies -- 6. Molecular Docking and Computational in silico Investigations of Metal-Based Drug Agents -- 7.Biochemical Mechanistic Pathway of Cell Death Induced by Metal-Based Chemotherapeutic Agents -- 8.Combination Drug Strategies for Targeting Specific Biochemical Pathways for Superior Therapeutic Potency -- 9. Advanced Drug Delivery Strategies for Metal-Based Anticancer Drugs -- 10. Endoplasmic Reticulum(ER) Targeted Metal-Based Anticancer Chemotherapeutic Agents -- 11.Progress and Future Projections in Metal-Based Polymeric Anticancer Compounds -- 12. Conclusions. | |
| 520 | |a This book reviews the potential of metallodrugs against different cancer. It summarizes the classification of metal-based anti-cancer drugs, their plausible biochemical and mechanistic pathways, combining drug strategies for hitting multiple therapeutic targets at the intracellular level, and advanced drug delivery strategies. The book covers the metallodrugs for the efficacious treatment of diverse cancerous strains and recent advances in drug delivery strategies that are used for developing these metal-based therapeutics as potent anticancer agents in vitro and in vivo. The book also covers different biophysical and analytical techniques for studying metal-ligand and metal-macromolecular interactions. The book further presents the recent examples of metallomics studies on the different types of cell death induced by metal-based anticancer drugs, especially on the three major forms of programmed cell death (PCD) in mammalian cells: apoptosis, autophagy, and regulated necrosis, also called necroptosis. Lastly, the book explores the modulation of reactive oxygen species (ROS) by metallodrugs. | ||
| 532 | 8 | |a Accessibility summary: This PDF does not fully comply with PDF/UA standards, but does feature limited screen reader support, described non-text content (images, graphs), bookmarks for easy navigation and searchable, selectable text. Users of assistive technologies may experience difficulty navigating or interpreting content in this document. We recognize the importance of accessibility, and we welcome queries about accessibility for any of our products. If you have a question or an access need, please get in touch with us at accessibilitysupport@springernature.com. | |
| 532 | 8 | |a No reading system accessibility options actively disabled | |
| 532 | 8 | |a Publisher contact for further accessibility information: accessibilitysupport@springernature.com | |
| 650 | 0 | |a Cancer |x Treatment. | |
| 650 | 0 | |a Cancer. | |
| 650 | 0 | |a Metabolism. | |
| 650 | 0 | |a Biochemistry. | |
| 650 | 1 | 4 | |a Cancer Therapy. |
| 650 | 2 | 4 | |a Cancer Metabolism. |
| 650 | 2 | 4 | |a Biochemistry. |
| 700 | 1 | |a Tabassum, Sartaj. |e author. |0 (orcid)0000-0002-5301-898X |1 https://orcid.org/0000-0002-5301-898X |4 aut |4 http://id.loc.gov/vocabulary/relators/aut | |
| 700 | 1 | |a Khan, Huzaifa Yasir. |e author. |4 aut |4 http://id.loc.gov/vocabulary/relators/aut | |
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