Chemistry and Biology of O-GlcNAcylation
O-linked N-acetylglucosamine (O-GlcNAc) is a prevalent post-translational modification of numerous intracellular proteins. This modification has recently emerged as a key regulator of various important biological processes, including gene transcription, stress response, metabolic homeostasis, and im...
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| Médium: | Elektronický zdroj E-kniha |
| Jazyk: | angličtina |
| Vydáno: |
Singapore :
Springer Nature Singapore : Imprint: Springer,
2024.
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| Vydání: | 1st ed. 2024. |
| Témata: | |
| On-line přístup: | https://doi.org/10.1007/978-981-97-4864-8 |
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| Shrnutí: | O-linked N-acetylglucosamine (O-GlcNAc) is a prevalent post-translational modification of numerous intracellular proteins. This modification has recently emerged as a key regulator of various important biological processes, including gene transcription, stress response, metabolic homeostasis, and immune regulation. Given the critical role of O-GlcNAc in normal physiology, increasing evidence has now demonstrated that deregulation of O-GlcNAc is closely associated with the development and progression of various diseases, including neurodegeneration, cardiovascular disease, and cancer. This book provides a comprehensive overview of the current progress and understanding of this modification in biology, and likely provides new research directions in the future. |
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| Fyzický popis: | 1 online resource (VII, 178 p. 44 illus.). 39 illus. in color. |
| ISBN: | 9789819748648 |
| DOI: | 10.1007/978-981-97-4864-8 |