Metal-Responsive Base Pair Switching of Ligand-type Uracil Nucleobases
In this thesis, the author proposes "metal-responsive base pair switching" of ligand-modified nucleobases as a novel tool for stimuli-responsive control of DNA assemblies. It is written to demonstrate broad applicability of the base pair switching in dynamic DNA nanotechnology and inspire...
שמור ב:
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| מחבר תאגידי: | |
| פורמט: | אלקטרוני ספר אלקטרוני |
| שפה: | אנגלית |
| יצא לאור: |
Singapore :
Springer Nature Singapore : Imprint: Springer,
2024.
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| מהדורה: | 1st ed. 2024. |
| סדרה: | Springer Theses, Recognizing Outstanding Ph.D. Research,
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| נושאים: | |
| גישה מקוונת: | https://doi.org/10.1007/978-981-99-9400-7 |
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| סיכום: | In this thesis, the author proposes "metal-responsive base pair switching" of ligand-modified nucleobases as a novel tool for stimuli-responsive control of DNA assemblies. It is written to demonstrate broad applicability of the base pair switching in dynamic DNA nanotechnology and inspire researchers to use this technique. Based on specific interactions between ligand-type nucleobases and target metal ions, in this volume, DNA hybridization was dynamically controlled through strand displacement reactions. The base pair switching was further applied to develop metal-dependent DNA molecular machines. This novel strategy for stimuli-responsive regulation of DNA assemblies will greatly expand the scope of dynamic DNA nanotechnology. This volume uniquely features importance of elaborate molecular design based on chemistry for imparting stimuli responsiveness to DNA assemblies. |
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| תיאור פיזי: | 1 online resource (XVII, 125 p. 111 illus.). 101 illus. in color. |
| ISBN: | 9789819994007 |
| ISSN: | 2190-5061 |
| DOI: | 10.1007/978-981-99-9400-7 |