MicroRNA in human infectious diseases /

This book, edited by Vijay Kumar Prajapati and Rupal Ojha, explores the role of microRNAs (miRNAs) in human infectious diseases. It delves into miRNA biogenesis, their functions, and pathological effects when dysregulated. The text highlights miRNAs' involvement in various cancers, including br...

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Altri autori: Prajapati, Vijay Kumar (Redattore), Ojha, Rupal (Redattore)
Natura: Elettronico eBook
Lingua:inglese
Pubblicazione: London : Academic Press, 2024.
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Accesso online:ScienceDirect
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245 0 0 |a MicroRNA in human infectious diseases /  |c edited by Vijay Kumar Prajapati, Rupal Ojha. 
264 1 |a London :  |b Academic Press,  |c 2024. 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
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505 8 |a I. Introduction of MiRNAs -- 1 Paradigms in miRNA biogenesis pathways -- 1.1 Introduction -- 1.2 miRNA biogenesis -- 1.2.1 Canonical pathway -- 1.2.1.1 Transcription of miRNA -- 1.2.1.2 Cleavage by Drosha microprocessor unit -- 1.2.1.3 Nuclear export -- 1.2.1.4 Dicing -- 1.2.1.5 RISC assembly -- 1.2.2 Noncanonical pathway -- 1.2.2.1 Drosha-independent pathway -- 1.2.2.1.1 MiRtrons -- 1.3 RNA-derived miRNAs -- 1.4 tRNA-derived miRNAs -- 1.5 tRNase Z-dependent pathway -- 1.6 Short-hairpin RNAs (endo-shRNAs)-derived miRNAs -- 1.6.1 Dicer-independent pathway -- 1.7 Functions of miRNA biogenesis -- 1.8 Pathological effects of dysregulation in miRNA biogenesis -- 1.8.1 Canonical pathway dysregulation -- 1.8.2 Noncanonical pathway -- 1.9 Future direction  |7 Generated by AI 
520 |a This book, edited by Vijay Kumar Prajapati and Rupal Ojha, explores the role of microRNAs (miRNAs) in human infectious diseases. It delves into miRNA biogenesis, their functions, and pathological effects when dysregulated. The text highlights miRNAs' involvement in various cancers, including breast and gynecologic cancers, and their diagnostic and therapeutic significance. It also examines miRNAs in bacterial and viral infections, such as respiratory infections, arboviral diseases, dengue, Ebola, COVID-19, and oncogenic viruses. The book aims to provide insights for researchers and professionals interested in the biomedical applications of miRNAs, offering a comprehensive analysis of their potential as diagnostic biomarkers and therapeutic targets.  |7 Generated by AI 
650 0 |a Communicable diseases  |x Genetic aspects. 
650 0 |a MicroRNA. 
650 2 |a MicroRNAs  |0 (DNLM)D035683 
650 6 |a Maladies infectieuses  |0 (CaQQLa)201-0001354  |x Aspect génétique.  |0 (CaQQLa)201-0377534 
650 6 |a MicroARN.  |0 (CaQQLa)000265128 
700 1 |a Prajapati, Vijay Kumar,  |e editor. 
700 1 |a Ojha, Rupal,  |e editor. 
776 0 8 |i Print version:  |z 0323996612  |z 9780323996617  |w (OCoLC)1391432561 
856 4 0 |3 ScienceDirect  |u https://www.sciencedirect.com/science/book/9780323996617