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MicroRNA in human infectious diseases /

This book, edited by Vijay Kumar Prajapati and Rupal Ojha, explores the role of microRNAs (miRNAs) in human infectious diseases. It delves into miRNA biogenesis, their functions, and pathological effects when dysregulated. The text highlights miRNAs' involvement in various cancers, including br...

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Dades bibliogràfiques
Altres autors: Prajapati, Vijay Kumar (Editor), Ojha, Rupal (Editor)
Format: Electrònic eBook
Idioma:anglès
Publicat: London : Academic Press, 2024.
Matèries:
Communicable diseases > Genetic aspects.
MicroRNA.
MicroRNAs
Maladies infectieuses > Aspect génétique.
MicroARN.
Accés en línia:ScienceDirect
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Taula de continguts:
  • I. Introduction of MiRNAs
  • 1 Paradigms in miRNA biogenesis pathways
  • 1.1 Introduction
  • 1.2 miRNA biogenesis
  • 1.2.1 Canonical pathway
  • 1.2.1.1 Transcription of miRNA
  • 1.2.1.2 Cleavage by Drosha microprocessor unit
  • 1.2.1.3 Nuclear export
  • 1.2.1.4 Dicing
  • 1.2.1.5 RISC assembly
  • 1.2.2 Noncanonical pathway
  • 1.2.2.1 Drosha-independent pathway
  • 1.2.2.1.1 MiRtrons
  • 1.3 RNA-derived miRNAs
  • 1.4 tRNA-derived miRNAs
  • 1.5 tRNase Z-dependent pathway
  • 1.6 Short-hairpin RNAs (endo-shRNAs)-derived miRNAs
  • 1.6.1 Dicer-independent pathway
  • 1.7 Functions of miRNA biogenesis
  • 1.8 Pathological effects of dysregulation in miRNA biogenesis
  • 1.8.1 Canonical pathway dysregulation
  • 1.8.2 Noncanonical pathway
  • 1.9 Future direction

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