Ureases : functions, classes, and applications /

Ureases: Foundations, Classes, and Applications provides a thorough, practical analysis of ureases-enzymes of growing relevance across a range of biotechnological applications and drug discovery. Unique in many aspects, ureases are one of the few enzymes to have nickel in their active sites. This bo...

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Andere auteurs: Ligabue-Braun, Rodrigo (Redacteur), Carlini, Célia Regina (Redacteur)
Formaat: Elektronisch E-boek
Taal:Engels
Gepubliceerd in: London, United Kingdom : Academic Press, 2024.
Reeks:Foundations and frontiers in enzymology series.
Onderwerpen:
Online toegang:ScienceDirect
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082 0 4 |a 572/.793  |2 23/eng/20240304  |1 https://id.oclc.org/worldcat/ddc/E3wBTrdrWPrChTxbbqBK6jckJK 
245 0 0 |a Ureases :  |b functions, classes, and applications /  |c edited by Rodrigo Ligabu-Braun, Celia Regina Carlini. 
264 1 |a London, United Kingdom :  |b Academic Press,  |c 2024. 
300 |a 1 online resource :  |b illustrations, color 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
340 |p illustration  |0 http://rdaregistry.info/termList/IllusContent/1014  |2 rdaill 
340 |g polychrome  |0 http://rdaregistry.info/termList/RDAColourContent/1003  |2 rdacc 
490 1 |a Foundations and frontiers in enzymology 
504 |a Includes bibliographic references and index. 
588 0 |a Online resource; title from PDF (viewed August 19, 2026). 
505 0 |a Introduction -- Historical aspects -- Classes and special cases -- Activation, catalysis, inhibition -- Health applications -- Biotechnological applications. 
520 |a Ureases: Foundations, Classes, and Applications provides a thorough, practical analysis of ureases-enzymes of growing relevance across a range of biotechnological applications and drug discovery. Unique in many aspects, ureases are one of the few enzymes to have nickel in their active sites. This book covers all aspects of this enzymatic class starting with foundational overview and then providing historical urease research and current state, from basic biochemistry to the use of ureases as hallmarks in enzymology, crystallography, and bioinorganic chemistry. The different classes of ureases, structurally diverse but chemically equivalent, are individually discussed. The multi-protein, multi-step activation of ureases (with chemical modification of residues, transport, and transfer of nickel ions) are examined in-depth, along with the catalytic mechanisms of ureolysis and its inhibitors. The final two sections of the book address multiple applications of ureases in health and biotechnology, respectively, going from gastric ulcer treatment to architectural uses in buildings and engineering. Future applications and next steps in research are also considered. 
650 0 |a Nickel enzymes. 
650 0 |a Nickel in the body. 
650 0 |a Urease. 
650 1 2 |a Urease  |0 (DNLM)D014510 
650 6 |a Uréase.  |0 (CaQQLa)201-0235279 
650 6 |a Enzymes à nickel.  |0 (CaQQLa)201-0263292 
650 6 |a Nickel dans l'organisme.  |0 (CaQQLa)201-0211223 
650 7 |a Urease  |2 fast  |0 (OCoLC)fst01162870 
700 1 |a Ligabue-Braun, Rodrigo,  |e editor.  |1 https://id.oclc.org/worldcat/entity/E39PCjtDHdxJcYRtXMxT3fMVmd 
700 1 |a Carlini, Célia Regina,  |e editor.  |1 https://id.oclc.org/worldcat/entity/E39PCjC4fq8PHMjKwhpQPBfm8d 
776 0 8 |i Print version:  |z 032391800X  |z 9780323918008  |w (OCoLC)1347696455 
830 0 |a Foundations and frontiers in enzymology series. 
856 4 0 |3 ScienceDirect  |u https://www.sciencedirect.com/science/book/9780323918008