Ionotropic cross-linking of biopolymers : applications in drug delivery /
Ionotropic Cross-Linking of Biopolymers: Applications in Drug Delivery provides in-depth insights and presents the latest advances in ionotropic cross-linked biopolymeric systems for drug delivery and related applications.
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| Outros autores: | , |
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| Formato: | eBook |
| Idioma: | inglés |
| Publicado: |
Amsterdam :
Elsevier,
2024.
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| Subjects: | |
| Acceso en liña: | ScienceDirect |
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| 008 | 240423s2024 ne o 000 0 eng d | ||
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| 020 | |a 0323996701 |q (electronic bk.) | ||
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| 020 | |z 0323961169 | ||
| 035 | |a (OCoLC)1430755312 | ||
| 050 | 4 | |a TP248.65.P62 | |
| 082 | 0 | 4 | |a 572/.33 |2 23/eng/20240508 |1 https://id.oclc.org/worldcat/ddc/E3RdC9wxW6GyVytpgWxTQHPv8h |
| 245 | 0 | 0 | |a Ionotropic cross-linking of biopolymers : |b applications in drug delivery / |c edited by Amit Kumar Nayak, Md Saquib Hasnain. |
| 260 | |a Amsterdam : |b Elsevier, |c 2024. | ||
| 300 | |a 1 online resource | ||
| 505 | 0 | |a Front Cover -- Ionotropic Cross-Linking of Biopolymers -- Copyright Page -- Contents -- List of contributors -- 1 Introduction and fundamentals -- 1 Ionotropic cross-linking of biopolymers: basics and mechanisms -- 1.1 Introduction -- 1.2 Ionotropic gelation technique -- 1.3 Counter-ions (ionic cross-linkers) for ionotropic gelation -- 1.4 Some common ionic biopolymers and their ionotropic gelations -- 1.4.1 Alginates -- 1.4.2 Pectins -- 1.4.3 Gellan gum -- 1.4.4 Chitosan -- 1.4.5 Carrageenan -- 1.4.6 Dextran -- 1.4.7 Carboxymethyl polysaccharides -- 1.5 Formation of polyelectrolyte complexes via ionotropic gelations -- 1.6 Ionotropically gelled biopolymeric systems in drug delivery -- 1.7 Conclusion -- References -- 2 Fundamentals and applications of ionic biopolymers -- 2.1 Introduction -- 2.2 Properties and advantages of ionic biopolymers -- 2.3 Challenges and limitations of ionic biopolymers -- 2.4 Preparation of Ionic Biopolymers -- 2.4.1 Polysaccharide/polysaccharide blends -- 2.4.2 Polysaccharide/polypeptide blends -- 2.4.3 Polysaccharide/bioplastic blends -- 2.5 Incorporation of pharmaceutical ingredients into biopolymer-based drug-delivery systems using ionic liquids -- 2.6 Strategies for assimilating pharmaceutical ingredients into biopolymer-based drug-delivery systems using ionic liquids -- 2.7 Electrospinning of biopolymer composites using ionic liquids -- 2.8 Enzyme-catalyzed processes in ionic liquids for biopolymer modification -- References -- 3 Ionotropic cross-linking methods for different types of biopolymeric hydrogels -- 3.1 Introduction -- 3.2 Preparation of hydrogels -- 3.2.1 Chemical gelation -- 3.2.2 Physical gelation -- 3.2.2.1 Ionotropic gelation -- 3.2.2.2 Chitosan ionic gelation -- 3.2.2.2.1 Alginate gelation -- 3.2.2.2.2 Pectin -- 3.2.2.2.3 Biomedical application -- 3.3 Conclusion -- References. | |
| 505 | 8 | |a 4 Ionotropic gelation in advanced drug delivery -- 4.1 Introduction -- 4.2 Biopolysaccharides -- 4.2.1 Definition -- 4.2.2 Properties -- 4.2.3 Composition -- 4.2.4 Classifications -- 4.2.4.1 By structure -- 4.2.4.1.1 Homopolysaccharides -- 4.2.4.1.2 Heteropolysaccharides -- 4.2.4.2 By source -- 4.2.4.3 By functions -- 4.3 Industrial applications of biopolysaccharides -- 4.4 Biomaterials-based hydrogels -- 4.4.1 Definition of hydrogel -- 4.4.2 Preparation techniques of hydrogels -- 4.4.3 Advantages of hydrogels -- 4.4.4 Hydrogels applications -- 4.5 Hydrogels based on biopolysaccharides and its potential application in drugs delivery -- 4.6 Conclusion -- References -- 2 Ionotropically cross-linked biopolymers -- 5 Utilizing alginate-based delivery systems for anticancer therapeutics -- 5.1 Introduction -- 5.2 Alginate delivery systems -- 5.2.1 Alginate delivery systems used against colon cancer -- 5.2.2 Alginate delivery systems against breast and hepatic cancer -- 5.2.3 Alginate delivery systems used in various cell lines -- 5.3 Conclusion -- References -- 6 Ionotropically crosslinked pectinate-based systems for drug delivery -- 6.1 Introduction -- 6.2 Pectin -- 6.2.1 Occurrence and structure -- 6.2.2 Physical and chemical behavior -- 6.2.3 Crosslinking of pectin -- 6.2.4 Factors affecting crosslinking -- 6.2.5 Types of crosslinking -- 6.2.5.1 Physical crosslinking -- 6.2.5.2 Chemical crosslinking -- 6.2.5.3 Ionotropic crosslinking -- 6.2.5.4 Miscellaneous crosslinking -- 6.2.6 Properties of crosslinked pectin (pectinate) -- 6.3 Applications of pectinate in drug delivery systems -- 6.3.1 pH-responsive drug delivery systems -- 6.3.2 Colon-specific targeting drug delivery systems -- 6.3.3 Floating drug delivery systems -- 6.3.4 Pulsatile drug delivery systems -- 6.3.5 Miscellaneous drug delivery systems -- 6.4 Current challenges and future prospects. | |
| 505 | 8 | |a 9.8.2 Swelling and charge density -- 9.8.3 Ionic cross-linkers -- 9.9 Ionotropical cross-linked carboxymethylated gums-based systems in drug delivery -- 9.9.1 Carboxymethylated xanthan gum -- 9.9.2 Carboxymethylated guar gum -- 9.9.3 Miscellaneous -- 9.10 Conclusion -- References -- 10 Starches-blended ionotropically cross-linked biopolymeric matrices for sustained drug release -- 10.1 Introduction -- 10.1.1 Overview on starch -- 10.2 Ionotropic gelation of starch -- 10.3 Drug delivery applications -- 10.3.1 Rice starch -- 10.3.2 Jackfruit seed starch -- 10.3.3 Potato starch -- 10.3.4 Arrowroot -- 10.3.5 Cassava starch -- 10.3.6 Other starch -- 10.3.7 Modified starch -- 10.4 Other applications -- 10.5 Future remarks and conclusions -- Acknowledgments -- References -- 3 Ionotropically cross-linked biopolymeric systems -- 11 Ionotropically cross-linked polymeric nanoparticles for drug delivery -- 11.1 Introduction -- 11.2 Cross-linking technique for polymeric nanodrug delivery systems -- 11.2.1 Types of cross-linking technique -- 11.2.2 Hydrogel as cross-linked polymer -- 11.2.3 The importance of cross-linked polymeric nanoparticles for drug delivery -- 11.3 Ionotropic cross-linking technique -- 11.3.1 The mechanism of ionotropic cross-linking technique -- 11.3.2 Factors affecting preparation of ionotropically cross-linked polymeric nanoparticles -- 11.3.2.1 Effect of concentration -- 11.3.2.2 Effect of polyanion -- 11.3.2.3 Effect of surfactant -- 11.3.2.4 Effect of sonication -- 11.3.2.5 Temperature -- 11.3.2.6 pH of cross-linking solution -- 11.3.3 Ionotropic cross-linked polymeric nanoparticles -- 11.3.3.1 Chitosan -- 11.3.3.2 Alginate -- 11.3.3.3 Other polymeric species -- 11.4 Applications -- 11.5 Conclusion -- References -- 12 Ionotropically cross-linked polymeric microparticles for drug delivery -- 12.1 Introduction. | |
| 505 | 8 | |a 12.2 Polymers in ionotropic gelation for drug delivery -- 12.2.1 Chitosan -- 12.2.2 Alginate -- 12.3 Methods of ionotropic gelation -- 12.4 Specific drug delivery applications of ionotropic-gelated microparticles -- 12.4.1 Controlled drug delivery -- 12.4.2 Targeted drug delivery -- 12.4.3 Vaccine delivery -- 12.4.4 Bioactive phytochemical compounds from plant -- 12.4.5 Encapsulation of probiotics -- 12.5 Evaluation of microparticles prepared by ionotropic gelation -- 12.5.1 Polymer-drug compatibility -- 12.5.1.1 Fourier transform infrared -- 12.5.1.2 Thermoanalytical methods -- 12.5.1.3 X-ray diffraction spectroscopy -- 12.5.2 Morphology -- 12.5.3 Zeta potential analysis -- 12.5.4 Porosity and density -- 12.5.5 Flow properties and compressibility index -- 12.5.6 Swelling index and erosion -- 12.5.7 Drug entrapment efficiency -- 12.5.8 Drug release study -- 12.5.8.1 Using dissolution test apparatus -- 12.5.8.2 Using container -- 12.5.8.3 Dialysis membrane method -- 12.5.9 Release mechanism -- 12.5.10 Mechanical strength of microparticles -- 12.6 Conclusion -- Conflict of interest -- References -- 13 Ionotropic cross-linked polymeric beads for drug delivery and in vitro applications -- 13.1 Introduction -- 13.2 Ionotropic polymers: basic mechanisms and processing techniques -- 13.2.1 Dripping method -- 13.2.2 Vibrating nozzle or laminar jet breakup -- 13.2.3 Mechanical cutting or jet cutter technology -- 13.2.4 Electrohydrodynamic atomization -- 13.3 Classification of ionotropic biopolymers -- 13.3.1 Alginate -- 13.3.2 Chitosan -- 13.3.3 Carboxymethyl cellulose -- 13.3.4 Gellan gum -- 13.4 Applications -- 13.4.1 Drug delivery -- 13.4.2 In vitro applications -- Acknowledgments -- References -- 14 Clay-reinforced ionotropically cross-linked biopolymeric matrices for drug release -- 14.1 Introduction. | |
| 520 | |a Ionotropic Cross-Linking of Biopolymers: Applications in Drug Delivery provides in-depth insights and presents the latest advances in ionotropic cross-linked biopolymeric systems for drug delivery and related applications. | ||
| 650 | 0 | |a Biopolymers. | |
| 650 | 0 | |a Drug delivery systems. | |
| 650 | 0 | |a Ion channels. | |
| 650 | 2 | |a Biopolymers |0 (DNLM)D001704 | |
| 650 | 2 | |a Drug Delivery Systems |0 (DNLM)D016503 | |
| 650 | 2 | |a Alginates |x therapeutic use |0 (DNLM)D000464Q000627 | |
| 650 | 2 | |a Drug Liberation |0 (DNLM)D065546 | |
| 650 | 2 | |a Ion Channels |0 (DNLM)D007473 | |
| 650 | 6 | |a Biopolymères. |0 (CaQQLa)201-0127997 | |
| 650 | 6 | |a Systèmes d'administration de médicaments. |0 (CaQQLa)000260397 | |
| 650 | 6 | |a Médicaments |x Libération. |0 (CaQQLa)000299953 | |
| 650 | 6 | |a Canaux ioniques. |0 (CaQQLa)201-0145111 | |
| 650 | 7 | |a Biopolymers |2 fast |0 (OCoLC)fst00832670 | |
| 650 | 7 | |a Drug delivery systems |2 fast |0 (OCoLC)fst00898667 | |
| 650 | 7 | |a Ion channels |2 fast |0 (OCoLC)fst00978573 | |
| 700 | 1 | |a Nayak, Amit Kumar, |d 1979- |1 https://id.oclc.org/worldcat/entity/E39PCjFkB7XHcxv7F6QfCVQ3w3 | |
| 700 | 1 | |a Hasnain, Md Saquib, |d 1984- |1 https://id.oclc.org/worldcat/entity/E39PCjJqQvwV7bBHC8mPk9Gk8P | |
| 776 | 0 | 8 | |i Print version: |z 0323961169 |z 9780323961165 |w (OCoLC)1342621440 |
| 856 | 4 | 0 | |3 ScienceDirect |u https://www.sciencedirect.com/science/book/9780323961165 |