Atlas of hematopathology with 100 case studies /

This comprehensive medical atlas, authored by Faramarz Naeim and colleagues, provides an in-depth exploration of hematological structures and conditions. It features 100 case studies detailing disorders of the bone marrow, white and red blood cells, and platelets. The book covers a wide array of top...

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Bibliographic Details
Main Author: Naeim, Faramarz
Other Authors: Rao, P. Nagesh, Song, Sophie X.
Format: eBook
Language:English
Published: [S.l.] : Academic Press, 2024.
Subjects:
Online Access:ScienceDirect
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Table of Contents:
  • Front Cover
  • Atlas of Hematopathology with 100 Case Studies
  • Atlas of Hematopathology with 100 Case Studies
  • Copyright
  • Contents
  • Preface
  • Acknowledgment
  • 1
  • Hematology associated structures
  • Bone marrow
  • Bone marrow sample preparation
  • Hematopoietic components in normal bone marrow
  • Myeloid series
  • Granulocytic lineage
  • Mast cells
  • Monocytic lineage
  • Dendritic cells
  • Erythroid lineage
  • Megakaryocytic lineage
  • Lymphocytic lineage
  • Other bone marrow cells
  • Blood
  • Red blood cells
  • White blood cells
  • Platelets
  • Lymph nodes
  • Follicular structures
  • The paracortex
  • The medulla
  • Spleen
  • White pulp
  • Marginal zone
  • Red pulp
  • Extramedullar hematopoiesis
  • Additional resources
  • 2
  • Disorders of bone marrow structure and function
  • Hypocellular bone marrows
  • Inherited bone marrow failure syndromes
  • Fanconi anemia
  • Morphology
  • Genetics
  • Dyskeratosis congenita
  • Morphology
  • Genetics
  • Shwachman-Diamond syndrome
  • Morphology/laboratory findings
  • Genetics
  • Diamond-Blackfan anemia
  • Morphology and laboratory findings
  • Genetics
  • Amegakaryocytosis
  • Morphology and laboratory findings
  • Genetics
  • Acquired aplastic anemia
  • Morphology and laboratory findings
  • Genetics
  • Paroxysmal nocturnal hemoglobinuria
  • Morphology and laboratory findings
  • Flow cytometry
  • Genetics
  • Gelatinous transformation of bone marrow
  • Post chemotherapy and radiation changes
  • Bone marrow changes post stem cell transplantation
  • Differential diagnosis
  • Hypercellular bone marrows
  • Reactive granulocytic hyperplasia
  • Reactive erythroid hyperplasia
  • Granulomas-reactive histiocytic hyperplasia
  • Bone marrow metastasis
  • Other bone marrow lesions
  • Bone marrow necrosis
  • Amyloidosis
  • Bone marrow fibrosis
  • Additional resources.
  • 3
  • Disorders of white blood cells and platelets
  • Qualitative abnormalities in the granulocytic series
  • Toxic granulation
  • Dohle inclusion bodies
  • May-Hegglin anomaly
  • Alder-Reilly anomaly
  • Chediak-Higashi syndrome
  • Pelger-Huet anomaly
  • Hypersegmented and dysplastic neutrophils
  • Quantitative abnormalities in the granulocytic series
  • Neutrophilia
  • Eosinophilia
  • Basophilia
  • Neutropenia
  • Monocytosis and monocytopenia
  • Monocytosis
  • Monocytopenia
  • Lymphocytosis and lymphocytopenia
  • Lymphocytosis
  • Infectious mononucleosis
  • Morphology and laboratory findings
  • Laboratory findings
  • Genetics
  • Differential diagnosis
  • Persistent polyclonal B-cell lymphocytosis
  • Lymphocytopenia
  • Quantitative abnormalities in platelets
  • Thrombocytosis
  • Thrombocytopenia
  • Autoimmune thrombocytopenic purpura
  • Morphology and laboratory findings
  • Differential diagnosis
  • Drug-induced immune thrombocytopenia
  • Posttransfusion purpura
  • Thrombotic thrombocytopenic purpura/hemolytic uremic syndrome
  • Morphology and laboratory findings
  • Differential diagnosis
  • Qualitative disorders of platelets
  • Bernard-Soulier syndrome
  • Morphology and laboratory findings
  • Genetics
  • Differential diagnosis
  • Glanzmann thrombasthenia
  • Morphology and immunophenotype
  • Molecular and cytogenetic features
  • Differential diagnosis
  • Wiskott-Aldrich syndrome
  • Dense granule deficiency
  • Alpha-granule deficiency
  • Acquired platelet disorders
  • Drug-induced platelet disorders
  • Aspirin
  • Beta-lactam antibiotics
  • Additional resources
  • 4
  • Disorders of red blood cells
  • Abnormal morphology
  • Congenital dyserythropoietic anemias
  • CDA type I
  • CDA type II
  • CDA type III
  • CDA group IV
  • CDA group V
  • CDA group VI
  • Morphology and laboratory findings
  • Macrocytic anemias
  • Megaloblastic anemias
  • Folate deficiency.
  • Histiocytic disorders
  • Gaucher disease
  • Morphology and laboratory findings
  • Genetics
  • Differential diagnosis
  • Nieman-Pick disease
  • Morphology and laboratory findings
  • Genetics
  • Differential diagnosis
  • Chediak-Higashi syndrome
  • Histiocytic proliferations
  • Rosai-Dorfman disease (sinus histiocytosis with massive lymphadenopathy
  • Erdheim-Chester disease
  • Juvenile xanthogranuloma
  • ALK-positive histiocytosis
  • Hemophagocytic lymphohistiocytosis
  • Morphology and laboratory findings
  • Genetics
  • Differential diagnosis
  • Histiocytic sarcoma
  • Dendritic cell disorders
  • Langerhans cell histiocytosis
  • Morphology and laboratory findings
  • Genetics
  • Differential diagnosis
  • Langerhans cell sarcoma
  • Mature plasmacytoid dendritic cell proliferation (MPDCP) associated with myeloid neoplasm
  • Blastic plasmacytoid dendritic cell neoplasm
  • Morphology and laboratory findings
  • Genetics
  • Differential diagnosis
  • Interdigitating dendritic cell tumor
  • Morphology and laboratory findings
  • Genetics
  • Differential diagnosis
  • Additional resources
  • 7
  • Myeloproliferative neoplasms
  • Chronic myeloid leukemia
  • Morphologic and laboratory findings
  • Chronic phase
  • Blast phase
  • Immunophenotyping
  • Flow cytometry
  • Immunohistochemical stains
  • Genetics
  • Differential diagnosis
  • Polycythemia vera
  • Morphology and laboratory findings
  • Polycythemic phase
  • Spent phase and postpolycythemic myelofibrosis
  • Immunophenotype
  • Genetics
  • Primary myelofibrosis
  • Morphology and laboratory findings
  • Prefibrotic/early stage
  • Overt fibrotic stage
  • Genetics
  • Essential thrombocythemia
  • Morphology and laboratory findings
  • Genetics
  • Differential diagnosis
  • Chronic neutrophilic leukemia
  • Morphology and laboratory findings
  • Genetics
  • Differential diagnosis
  • Chronic eosinophilic leukemia.
  • Morphology and laboratory findings
  • Genetics
  • Differential diagnosis
  • Juvenile myelomonocytic leukemia
  • Morphology and laboratory findings
  • Immunophenotype and cytochemical stains
  • Flow cytometry (Fig. 7.31)
  • Immunohistochemistry and cytochemical stains
  • Genetics
  • MPN, not otherwise specified
  • Additional resources
  • 8
  • Mastocytosis
  • Classification
  • Cutaneous mastocytosis
  • Systemic mastocytosis
  • Mast cell sarcoma
  • Pathology
  • Morphology and laboratory findings
  • Immunophenotypic studies
  • Genetics
  • Differential diagnosis
  • Disorders with similar clinical manifestation but lack of histologic evidence of cutaneous or systemic mastocytosis
  • Disorders associated with increased mast cells or elevated serum tryptase
  • Additional resources
  • 9
  • Myelodysplastic neoplasms and myelodysplastic/myeloproliferative neoplasms
  • Myelodysplastic neoplasms
  • Classification
  • MDS with defining genetic abnormalities, and MDS, morphologically defined
  • Morphology
  • Dysplastic erythropoiesis
  • Dysplastic myelopoiesis
  • Dysplastic megakaryocytes and platelets
  • Immunophenotypic studies
  • Flow cytometry
  • Blast enumeration
  • Detection of immunophenotypic aberrancies and dysmaturation patterns
  • Immunohistochemical studies
  • Genetics
  • Cytogenetics
  • Molecular genetics
  • Other types of MDS
  • Therapy-related MDS
  • Childhood MDS
  • MDS with fibrosis
  • Nonclonal myelodysplasia
  • Autoimmune myelodysplasia
  • HIV-associated myelodysplasia
  • Paraneoplastic myelodysplasia
  • Myelodysplasia associated with heavy metal intoxication or deficiency
  • Myelodysplasia associated with chemotherapy, irradiation, or medication
  • Differential diagnosis
  • Myelodysplastic/myeloproliferative neoplasms
  • Chronic myelomonocytic leukemia
  • Morphology and laboratory findings
  • Immunophenotype and cytochemical stains.