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Green Approaches in Medicinal Chemistry for Sustainable Drug Design : Applications /

Guardat en:
Dades bibliogràfiques
Altres autors: Banik, Bimal K.
Format: eBook
Idioma:anglès
Publicat: San Diego : Elsevier, 2024.
Edició:2nd ed.
Col·lecció:Advances in Green and Sustainable Chemistry Series.
Matèries:
Pharmaceutical chemistry.
Chemistry, Pharmaceutical
Chimie pharmaceutique.
Pharmaceutical chemistry
Accés en línia:ScienceDirect
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Taula de continguts:
  • Front Cover
  • Green Approaches in Medicinal Chemistry for Sustainable Drug Design
  • Copyright Page
  • Contents
  • List of contributors
  • About the editor
  • Preface
  • Acknowledgment
  • 1 Chemical catalysis
  • 1 Green metal catalyzed reactions under sustainable conditions toward medicinally potent biomolecules
  • 1.1 Introduction
  • 1.2 C-C coupling reactions
  • 1.2.1 Suzuki-Miyaura coupling
  • 1.2.2 Negishi and Stille couplings
  • 1.2.3 Sonogashira coupling
  • 1.2.4 Heck coupling
  • 1.2.5 Decarboxylative C-C coupling
  • 1.2.6 Kumada-Corriu coupling
  • 1.2.7 Arylation of enolates
  • 1.2.8 Hayashi-Miyaura reaction
  • 1.2.9 Aromatic cyanation
  • 1.3 Conclusion
  • References
  • Further reading
  • 2 Graphene oxide and modified graphene oxide-mediated synthesis of medicinally active compounds
  • 2.1 Introduction
  • 2.2 One-pot multistep synthesis
  • 2.3 Dehydrogenative coupling reactions
  • 2.4 Oxidation and hydration reactions
  • 2.5 Ring-opening reactions
  • 2.6 Direct amidation of carboxylic acids with amines
  • 2.7 Conclusions
  • Acknowledgments
  • References
  • 3 Organocatalytic cycloaddition reaction: a gateway for molecular complexity
  • 3.1 Introduction
  • 3.2 [4+2] Cycloaddition reaction
  • 3.3 [4+2] Cycloaddition via iminium ion activation
  • 3.4 [4+2] Cycloaddition via enamine activation
  • 3.5 Conclusions
  • Acknowledgments
  • References
  • 2 Biocatalysis
  • 4 Baker's yeast-induced synthesis of medicinally important compounds
  • 4.1 Introduction
  • 4.1.1 Procedure for generation of Baker's yeast
  • 4.1.2 Properties of Baker's yeast
  • 4.1.3 Advantages of Baker's yeast
  • 4.1.4 Methods involved in organic synthesis via Baker's yeast
  • 4.1.5 Role of Baker's yeast in organic synthesis
  • 4.1.5.1 Synthesis of heterocyclic compounds
  • 4.1.5.2.5 Reduction of methyl acetoacetate
  • 4.1.5.3 Baker's yeast mediated reaction and synthesis of bioactive compounds
  • 4.1.5.3.1 Synthesis of cinnamyl acetate
  • 4.1.5.3.2 Synthesis of fenfluramine
  • 4.1.5.4 Synthesis of artemisinin with Baker's yeast
  • 4.1.5.5 Baker's yeast mediated reduction of carvone
  • 4.1.5.6 Cyclization of Squalene-like substrates
  • 4.1.5.7 Baker's yeast assisted synthesis of ephedrine
  • 4.1.5.8 Baker's yeast assisted synthesis of denopamine
  • 4.2 Future perspectives
  • 4.3 Conclusions
  • List of abbreviations
  • References

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