Spirooxindole : chemistry, synthesis, characterization and biological significance /
This book, edited by Gautam Patel, Vraj R. Shah, Tuan Anh Nguyen, and Kalim Deshmukh, offers a comprehensive exploration of spirooxindole chemistry, focusing on synthesis and biological significance. It delves into various synthetic methods, including cycloaddition reactions and regioselective synth...
Sábháilte in:
| Formáid: | Ríomhleabhar |
|---|---|
| Teanga: | Béarla |
| Foilsithe / Cruthaithe: |
[S.l.] :
Elsevier,
2024.
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| Ábhair: | |
| Rochtain ar líne: | ScienceDirect |
| Clibeanna: |
Cuir clib leis
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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MARC
| LEADER | 00000cam a2200000 a 4500 | ||
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| 001 | on1439566353 | ||
| 003 | OCoLC | ||
| 005 | 20260915095220.0 | ||
| 006 | m o d | ||
| 007 | cr |n||||||||| | ||
| 008 | 240616s2024 xx o 000 0 eng d | ||
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| 019 | |a 1441723496 | ||
| 020 | |a 9780443223259 |q (electronic bk.) | ||
| 020 | |a 0443223254 |q (electronic bk.) | ||
| 020 | |z 9780443223242 | ||
| 020 | |z 0443223246 | ||
| 035 | |a (OCoLC)1439566353 |z (OCoLC)1441723496 | ||
| 050 | 4 | |a QD400 | |
| 082 | 0 | 4 | |a 615.1/9 |2 23/eng/20240625 |1 https://id.oclc.org/worldcat/ddc/E4bTrbhdcjy3hWWpQKYr7x4mXb |
| 245 | 0 | 0 | |a Spirooxindole : |b chemistry, synthesis, characterization and biological significance / |c edited by Gautam Patel [and more]. |
| 260 | |a [S.l.] : |b Elsevier, |c 2024. | ||
| 300 | |a 1 online resource | ||
| 505 | 0 | |a Front Cover -- Spirooxindole -- Copyright Page -- Contents -- List of contributors -- About the editors -- Preface -- 1 Synthesis of spirooxindoles by [3+2] cycloadditions -- 1.1 Introduction -- 1.2 Cycloadditions of isatin-based dipolarophiles -- 1.3 [3+2] Cycloadditions of isatin-derived 1,3-dipoles -- 1.4 Cycloadditions of isatin-derived 1,3-dipoles and dipolarophiles for dispirooxindoles -- 1.5 Intramolecular [3+2] cycloadditions -- 1.6 Summary -- References -- 2 Synthesis of spirooxindoles under ultrasonication -- 2.1 Introduction | |
| 505 | 8 | |a 2.2 Construction of three member ring on C-3 carbon of oxindole -- 2.2.1 Synthesis of oxirane annulated spirooxindoles -- 2.3 Construction of five member ring on C-3 carbon oxindole -- 2.3.1 Synthesis of pyrrolidine annulated spirooxindoles -- 2.3.2 Synthesis of thiazolidinone ring annulated spirooxindoles -- 2.3.3 Synthesis of oxathiolanes ring annulated spirooxindoles -- 2.3.4 Synthesis of pyrazol ring annulated spirooxindoles -- 2.4 Construction of six member ring on C-3 carbon of oxindoles -- 2.4.1 Synthesis of pyran annulated spirooxindoles -- 2.4.1.1 Three-component reactions | |
| 505 | 8 | |a 2.4.1.2 Four component reactions -- 2.4.2 Synthesis of pyridine annulated spirooxindoles -- 2.4.3 Synthesis of naphthalene annulated spirooxindoles -- 2.4.4 Synthesis of quinazolinones annulated spirooxindoles -- 2.4.5 Synthesis of thiazine annulated spirooxindoles -- 2.4.6 Synthesis of oxazine annulated spirooxindoles -- 2.5 Construction of seven member ring on C-3 carbon -- 2.5.1 Synthesis of thiazepine ring annulated spirooxindoles -- 2.5.2 Synthesis of diazepine ring annulated spirooxindoles -- 2.6 Conclusion -- References | |
| 505 | 8 | |a 3 Organocatalyzed cycloaddition of N-2,2,2-trifluoroethylisatin ketimines for synthesis of CF3-containing spirooxindoles -- 3.1 Introduction -- 3.2 Organocatalyzed asymmetric [3+2] cycloaddition reaction of N-2,2,2-trifluoroethylisatin ketimines -- 3.2.1 Synthesis of CF3-containing monospiroxidindoles -- 3.2.1.1 Asymmetric [3+2] cycloaddition reactions with chained conjugated alkenes -- 3.2.1.2 Asymmetric [3+2] cycloaddition reactions with exocyclic olefins -- 3.2.2 Synthesis of CF3-containing dispiroxidindoles -- 3.2.2.1 Asymmetric [3+2] cycloaddition reactions with exocyclic olefins | |
| 505 | 8 | |a 3.2.2.2 Asymmetric [3+2] cycloaddition reactions with 3-metheneindolinones -- 3.2.3 Synthesis of CF3-containing pyrrolidine-fused spirocyclic dihydro-benzoheterocyclic compounds -- 3.2.4 Synthesis of other CF3-containing polycyclic compounds -- 3.3 Organocatalyzed asymmetric [4+3] cycloaddition reaction of N-2,2,2-trifluoroethylisatin ketimines -- 3.4 Conclusions -- References -- 4 Regio- and stereoselective synthesis of spirooxindole scaffold -- 4.1 Introduction -- 4.1.1 Network analysis about spirooxindoles -- 4.2 Regio- and stereoselective synthesis of spirooxindole scaffolds | |
| 520 | |a This book, edited by Gautam Patel, Vraj R. Shah, Tuan Anh Nguyen, and Kalim Deshmukh, offers a comprehensive exploration of spirooxindole chemistry, focusing on synthesis and biological significance. It delves into various synthetic methods, including cycloaddition reactions and regioselective syntheses, and examines the biological applications of spirooxindole derivatives, particularly their potential as anticancer agents. The authors aim to provide researchers and practitioners in chemistry and pharmaceutical sciences with detailed methodologies and insights into the therapeutic potential of spirooxindoles. The book is intended for an audience of chemists, pharmacologists, and researchers interested in synthetic organic chemistry and medicinal applications. |7 Generated by AI | ||
| 650 | 0 | |a Oxindoles. | |
| 650 | 7 | |a Oxindoles |2 fast |0 (OCoLC)fst02008799 | |
| 776 | 0 | 8 | |i Print version: |z 0443223246 |z 9780443223242 |w (OCoLC)1414458442 |
| 856 | 4 | 0 | |3 ScienceDirect |u https://www.sciencedirect.com/science/book/9780443223242 |