Kapak Resmi

Herbal formulations, phytochemistry and pharmacognosy /

Herbal Formulations, Phytochemistry and Pharmacognosy combines the principles of natural medicines with refined modern technology to illustrate and promote the development of more ecofriendly, better effective, easily available and affordable drug discovery processes.

Kaydedildi:
Detaylı Bibliyografya
Materyal Türü: Ekitap
Dil:İngilizce
Baskı/Yayın Bilgisi: Amsterdam : Elsevier, 2024.
Seri Bilgileri:Drug discovery update
Konular:
Herbs > Therapeutic use.
Drug discrimination (Pharmacology)
Pharmacognosy.
Materia medica, Vegetable.
Pharmacognosy
Phytotherapy
Herbes > Emploi en thérapeutique.
Discrimination de médicaments (Pharmacologie)
Pharmacognosie.
Phytothérapie.
MEDICAL / Pharmacology.
SCIENCE / Chemistry / Organic.
Herbs > Therapeutic use
Materia medica, Vegetable
Online Erişim:ScienceDirect
Etiketler: Etiketle
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İçindekiler:
  • Front Cover
  • Herbal Formulations, Phytochemistry and Pharmacognosy
  • Copyright Page
  • Contents
  • List of contributors
  • 1 Herbal formulations for the treatment of fungal infection
  • 1.1 Preamble
  • 1.2 Human fungal infection
  • 1.2.1 Classification and pathophysiology of fungal infection
  • 1.2.2 Medical devices and fungal infection
  • 1.2.3 Biofilm-a major issue
  • 1.2.4 Current antifungal treatments and resistance by fungal pathogen
  • 1.3 Role of herbs and their products in the management of fungal infection
  • 1.3.1 Garlic
  • 1.3.2 Clove
  • 1.3.3 Thyme
  • 1.3.4 Turmeric
  • 1.3.5 Tulsi
  • 1.3.6 Ginger
  • 1.4 Nano medicines for the treatment of fungal infection with special reference to herbs
  • 1.4.1 Polymeric and metallic nanoparticles
  • 1.4.2 Liposomes
  • 1.4.3 Solid lipid nanoparticles
  • 1.4.4 Nanostructured lipid carriers
  • 1.4.5 Nanoemulsion
  • 1.4.6 Ethosomes and niosomes
  • 1.4.7 Transferosomes
  • 1.5 Formulation strategies for the development of antifungal herbal preparations
  • 1.5.1 Cell wall of fungal pathogen
  • 1.5.2 Intervention in antifungal resistance
  • 1.5.3 Controlling the biofilm and other virulence factors
  • 1.5.4 Targeting the metabolic pathway and enzymes of fungal pathogen
  • 1.5.5 Targeting the fungal mitochondria
  • 1.5.6 Design of combination therapy
  • 1.5.7 Development of prophylactics
  • 1.6 Conclusion
  • 1.7 Future perspectives
  • Abbreviations
  • Acknowledgment
  • References
  • 2 Combination and formulation of Ghanaian herbal products for the treatment and management of disease as potent health tonic
  • 2.1 Introduction
  • 2.2 Common herbal dosage forms of the Ghanaian market
  • 2.2.1 Decoctions
  • 2.2.2 Infusions
  • 2.2.3 Tincture
  • 2.2.4 Herbal tablets
  • 2.2.5 Herbal capsules
  • 2.2.6 Herbal ointments
  • 2.2.7 Herbal balm
  • 2.2.8 Herbal paste
  • 2.2.9 Herbal creams
  • 2.2.10 Herbal soap.
  • 2.2.11 Herbal powders
  • 2.2.12 Herbal oils
  • 2.2.13 Herbal suppositories/pessaries
  • 2.2.14 Herbal glycerites
  • 2.2.15 Herbal lozenges
  • 2.3 Registration and promotion of formulated herbal medicinal products in Ghana
  • 2.4 Recommended herbal products by the Ministry of Health
  • 2.5 Reported efficacy of some herbal products on the Ghanaian market
  • 2.6 Reported quality, safety, and toxicity assessment of some herbal products in Ghana
  • 2.7 Reported phytochemical and pharmacognostic properties of some selected plants
  • 2.7.1 Xylopia aethiopica
  • 2.7.2 Paullinia pinnata
  • 2.7.3 Khaya senegalensis
  • 2.7.4 Cryptolepis sanguinolenta
  • 2.7.5 Allium sativum
  • 2.7.6 Aleo forex
  • 2.7.7 Cassia alata
  • 2.7.8 Zingiber officinale
  • 2.7.9 Rauvolfia vomitoria
  • 2.7.10 Aframomum melegueta
  • 2.7.11 Azadirachta indica
  • 2.8 Conclusion
  • References
  • 3 Emerging trends in herbal formulation based on medicinal plants and algae in cancer therapeutics: A modern era perspective
  • 3.1 Introduction
  • 3.2 Complex synergistic interaction of phytoconstituents of herbal formulations derived from terrestrial plants
  • 3.2.1 Polyphenols
  • 3.2.2 Terpenoids
  • 3.2.3 Alkaloids
  • 3.2.4 Phytosterol
  • 3.3 Complex synergistic interaction of various phytoconstituents derived from macroalgae and microalgae: current scenario o...
  • 3.4 Phytotherapeutics-emerging trends and bottlenecks
  • 3.5 Future aspects of herbal formulation in anticancer activities
  • References
  • 4 Synergistic effects of plant extracts for antimicrobial therapy
  • 4.1 Introduction
  • 4.2 Statistics of antimicrobial disease
  • 4.3 Plant metabolites used in antimicrobial therapy
  • 4.3.1 Phenols, polyphenols, and quinones
  • 4.3.2 Essential oils and terpenoids
  • 4.3.3 Alkaloids
  • 4.3.4 Polypeptides and lectins
  • 4.4 Epidemiology of microbial infection
  • 4.4.1 Etiology of sinus infection.
  • 4.4.2 Bacteriology
  • 4.4.3 Virology
  • 4.4.4 Fungology
  • 4.4.5 Persistent sinus infection
  • 4.4.6 Opportunist fungal disease
  • 4.5 Introduction to plant extracts used in antimicrobial therapy
  • 4.6 Disadvantages of synthetic antibiotics therapy over plant extracts
  • 4.7 Harmful effects of synthetic and semisynthetic antibiotics
  • 4.7.1 Antibiotics' toxicity
  • 4.7.2 Hypersensitivity adverse effects
  • 4.7.3 Hematologic adverse effects
  • 4.7.4 Neurologic adverse effects
  • 4.7.5 Gastrointestinal adverse effects
  • 4.7.6 Renal adverse effects
  • 4.7.7 Cardiac adverse effects
  • 4.7.8 Pulmonary adverse effects
  • 4.7.9 Hepatic adverse effects
  • 4.7.10 Accurate selection of relevant criteria to reduce the toxicity of antibiotics
  • 4.7.11 Bacterial resistance to antibiotics
  • 4.7.12 Natural compounds with antibacterial effect
  • 4.8 Future perspective
  • 4.9 Conclusions
  • Abbreviations
  • References
  • 5 Herbal formulation: An Ayurvedic treatment for human diseases
  • 5.1 Introduction
  • 5.1.1 Herbal formulation
  • 5.1.2 Phytochemistry of herbal formulations
  • 5.2 Herbal formulations for treating various diseases
  • 5.3 Herbal formulation: Tuvarak oil (chaulmoogra oil) for treating vitiligo
  • 5.3.1 Formulation composition
  • 5.3.2 Plant used to make Tuvarak oil
  • 5.3.2.1 Hydnocarpus laurifolia
  • 5.3.2.2 Acacia catechu
  • 5.3.3 Uses of Tuvarak or chaulmoogra oil
  • 5.3.4 Market price of the formulation
  • Abbreviation
  • Acknowledgment
  • References
  • 6 Antiinflammatory and analgesic activities of herbal formulation
  • 6.1 Introduction
  • 6.2 List of herbal formulations for antiinflammatory and analgesic activities
  • 6.2.1 Rumalaya
  • 6.2.2 Triphala
  • 6.2.3 Reosto
  • 6.2.4 Laghupanchamula
  • 6.2.5 Habbe gule aakh
  • 6.3 Phytoconstituents of herbal formulation for antiinflammatory and analgesic activities
  • 6.3.1 Essential oil.
  • 6.3.2 Alkaloids
  • 6.3.3 Polyphenol
  • 6.3.4 Glycosides
  • 6.3.5 Gum resins
  • 6.3.6 Polysaccharides
  • 6.4 Cytotoxicity evaluation of herbal formulations
  • 6.5 Trials of herbal formulations in various models
  • 6.6 Conclusion and future remarks
  • References
  • 7 Herbal antifungal formulations for controlling dandruff and seborrheic dermatitis
  • 7.1 Introduction
  • 7.1.1 Dandruff and seborrheic dermatitis
  • occurrence and global burden
  • 7.1.1.1 Dandruff
  • 7.1.2 Etiology of Malassezia-induced dandruff
  • 7.1.3 Malassazia's lipase and carbonic anhydrase-the drug targets
  • 7.1.4 Established lipase and carbonic anhydrase inhibitors
  • 7.1.5 Current antidandruff therapies and the limitations
  • 7.2 Traditional Indian remedies
  • 7.2.1 Oil-based formulations
  • 7.2.2 Soapberries and saponins
  • 7.2.3 pH modulators
  • 7.2.4 Antioxidants
  • 7.2.5 Other herbal products containing lipase inhibitory properties
  • 7.3 Summary and conclusion
  • References
  • 8 AYUSH-64: a potential immunomodulatory medicine for COVID-19
  • 8.1 Introduction
  • 8.2 Methods
  • 8.3 Results and discussion
  • 8.3.1 Recent clinical trials
  • 8.4 Conclusion
  • Funding
  • Conflict of interest
  • References
  • 9 Polyherbal formulation for the treatment of dengue
  • 9.1 Introduction
  • 9.2 Material and method
  • 9.2.1 Collection of plant materials
  • 9.2.2 Extraction of plant materials
  • 9.2.3 Phytochemical analysis of plant extract
  • 9.2.3.1 Test for carbohydrates
  • 9.2.3.2 Tests for proteins
  • 9.2.3.3 Test for alkaloids
  • 9.2.3.4 Test for flavonoids
  • 9.2.3.5 Test for phenolic compounds
  • 9.2.3.6 Test for amino acid
  • 9.2.3.7 Test for saponins
  • 9.2.4 Quantitative analysis of plant extract
  • 9.2.4.1 Total phenolic content
  • 9.2.4.2 Total tannin content
  • 9.2.4.3 Total condensed tannin content
  • 9.2.4.4 Total hydrolyzable tannin content.
  • 9.2.4.5 Total alkaloid content
  • 9.2.4.6 Total flavonoid content
  • 9.2.5 In vitro antioxidant test
  • 9.2.5.1 2,2-Diphenyl-1-picrylhydrazyl radical scavenging activity
  • 9.2.5.2 Ferric reducing antioxidant power assay
  • 9.2.6 Formulation development of plant extract
  • 9.2.6.1 Screening of solid adsorbent
  • 9.2.6.2 Procedure of screening of solid adsorbent
  • 9.2.7 Screening of solid adsorbent
  • 9.2.7.1 Angle of repose
  • 9.2.7.2 Bulk density
  • 9.2.7.3 Tapped density
  • 9.2.7.4 Carr's index
  • 9.2.7.5 Hausner's ratio
  • 9.2.8 Evaluation parameter of herbal capsule
  • 9.2.8.1 Physical characterization
  • 9.2.8.2 Determination of disintegration time
  • 9.2.8.3 Determination of uniformity of weight
  • 9.2.8.4 Determination of drug content in formulation
  • 9.2.9 Quantification of active constituents in extract
  • 9.2.9.1 Densitometric scanning
  • 9.2.10 Preparation of standard solution
  • 9.2.11 Calibration curve of Carpaine and Quercetin
  • 9.2.11.1 Preparation of test solutions
  • 9.2.12 Estimation of Carpine and Quercetin
  • 9.2.12.1 Validation of HPTLC method
  • 9.3 Result and discussion
  • 9.3.1 Quantitative analysis of plant extract
  • 9.3.1.1 Total phenolic content
  • 9.3.1.2 Total tannin content
  • 9.3.1.3 Total condensed tannin content
  • 9.3.1.4 Total hydrolyzable tannin content
  • 9.3.1.5 Total alkaloid content
  • 9.3.1.6 Total flavonoid content
  • 9.3.2 2,2-Diphenyl-1-picrylhydrazyl radical scavenging activity
  • 9.3.3 Ferric reducing antioxidant power assay
  • 9.3.4 Formulation of plant extract
  • 9.3.4.1 Screening of solid adsorbent
  • 9.3.5 Evaluation of herbal capsule
  • 9.3.5.1 Physical characterization of powder
  • 9.3.5.2 Determination of disintegration time
  • 9.3.5.3 Determination of uniformity of weight
  • 9.3.5.4 Determination of drug content in formulation
  • 9.3.5.5 Quantification of active constituents in extract.

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