Oxazole, isoxazole, benzoxazole-based drug discovery /
Oxazole, Isoxazole, Benzoxazole Based Drug Discovery offers complete coverage of oxazole and related molecules, both from natural and synthetic origin, with a focus on the reaction mechanisms, and medicinal, pharmacokinetic and computational aspects.
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| Glavni autori: | , , |
|---|---|
| Format: | Elektronički e-knjiga |
| Jezik: | engleski |
| Izdano: |
Amsterdam, Netherlands ; Cambridge, MA :
Elsevier,
[2025]
|
| Serija: | Heterocyclic drug discovery series
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| Teme: | |
| Online pristup: | ScienceDirect |
| Oznake: |
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| 082 | 0 | 4 | |a 615.19 |2 23 |1 https://id.oclc.org/worldcat/ddc/E4bTrbhdcjy3hWWpQKYr7x4mXb |
| 100 | 1 | |a Hussain, Erum Akbar, |e author. | |
| 245 | 1 | 0 | |a Oxazole, isoxazole, benzoxazole-based drug discovery / |c Erum Akbar Hussain, Ambreen Ghani, Zubi Sadiq. |
| 264 | 1 | |a Amsterdam, Netherlands ; |a Cambridge, MA : |b Elsevier, |c [2025] | |
| 300 | |a 1 online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 0 | |a Heterocyclic drug discovery series | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | |a Description based on online resource; title from digital title page (viewed on November 22, 2024). | ||
| 505 | 0 | |a Front Cover -- Oxazole, Isoxazole, Benzoxazole-Based Drug Discovery -- Copyright Page -- Contents -- 1 Introduction -- 1.1 Introduction -- 1.1.1 Natural sources -- 1.1.2 Marine sources -- 1.1.3 Terrestrial source -- 1.2 Extraction methods -- 1.3 Purification techniques and structure elucidation -- 1.3.1 Chemistry -- 1.3.2 Biological significance -- 1.3.3 Drug discovery and development -- References -- 2 Oxazoles -- 2.1 Introduction -- 2.2 General methods of synthesis of oxazole -- 2.2.1 Transition metal-catalyzed synthesis -- 2.2.2 Van Leusen approach for an oxazole ring | |
| 505 | 8 | |a 2.2.3 Robinson-Gabriel route toward oxazoles -- 2.2.4 Aza-Wittig approach for oxazole synthesis -- 2.2.5 Fischer synthesis of oxazole -- 2.3 Marketed drugs containing the oxazole ring -- 2.3.1 Oxaprozin -- References -- 3 Isoxazole -- 3.1 Introduction -- 3.2 General methods for synthesis of isoxazole -- 3.3 Marketed drugs containing isoxazole nucleus -- 3.3.1 Broxaterol -- 3.3.2 Isocarboxazid -- 3.3.3 Sulfamethoxazole -- 3.3.4 Zonisamide -- 3.3.5 Sulfisoxazole -- 3.3.6 Parecoxib sodium -- 3.3.7 Valdecoxib -- 3.3.8 Risperidone -- 3.3.9 Leflunomide -- 3.3.10 Danazol -- 3.3.11 Androisoxazole | |
| 505 | 8 | |a 3.3.12 Isoxazolyl penicillins: cloxacillin, dicloxacillin, flucloxacillin, and oxacillin -- References -- 4 Benzoxazole -- 4.1 Introduction -- 4.2 General approaches for the synthesis of benzoxazole -- 4.3 Marketed drugs containing benzoxazoles -- 4.3.1 Flunoxaprofen -- 4.3.2 Benoxaprofen -- 4.3.3 Zoxazolamine -- 4.3.4 Tafamidis -- References -- 5 Oxazolone -- 5.1 General methods for synthesis of oxazolone -- 5.1.1 Erlenmeyer synthesis -- 5.2 Marketed drugs containing the oxazolone nucleus -- 5.2.1 Chlorzoxazone -- 5.2.2 Cyclazodone -- 5.2.3 Thozalinone -- 5.2.4 Fenozolone -- References | |
| 505 | 8 | |a 6 Oxadiazole -- 6.1 Introduction -- 6.1.1 1,2,3-Oxadiazoles -- 6.1.2 1,2,4-Oxadiazole -- 6.1.3 1,3,4-Oxadiazole -- 6.2 General methods for synthesis of oxadiazoles -- 6.2.1 Synthesis of 1,2,4-oxadiazoles -- 6.2.1.1 Synthesis of 1,3,4-oxadiazoles -- 6.3 Marketed drugs having an oxadiazole scaffold -- 6.3.1 1,2,3-Oxadiazoles -- 6.3.2 Molsidomine -- 6.3.3 1,2,4-Oxadiazoles -- 6.3.4 Ataluren -- 6.3.5 Azilsartan medoxomil -- 6.3.6 Butalamine -- 6.3.7 Imolamine -- 6.3.8 Fasiplon -- 6.3.9 Opicapone -- 6.3.10 Ozanimod -- 6.3.11 Oxolamine -- 6.3.12 Prenoxdiazine -- 6.3.13 Proxazol citrate | |
| 505 | 8 | |a 6.3.14 Pleconaril -- 6.3.15 1,2,5-Oxadiazole -- 6.3.16 Furazabol -- 6.3.17 1,3,4-Oxadiazoles -- 6.3.18 Furamizole -- 6.3.19 Nesapidil -- 6.3.20 Raltegravir -- 6.3.21 Tiodazosin -- 6.3.22 Fenadiazole -- References -- 7 Oxazolidinone -- 7.1 Introduction -- 7.2 Synthetic approaches for oxazolidinone -- 7.2.1 Catalyst-free approaches for oxazolidinone -- 7.2.2 Catalyst-mediated approaches for oxazolidinones -- 7.2.3 Organocatalyst-mediated synthesis of oxazolidinone -- 7.3 Marketed drugs having the oxazolidinone scaffold -- 7.3.1 Terizidone -- 7.3.2 Metaxalone -- 7.3.3 Tedizolid phosphate | |
| 520 | |a Oxazole, Isoxazole, Benzoxazole Based Drug Discovery offers complete coverage of oxazole and related molecules, both from natural and synthetic origin, with a focus on the reaction mechanisms, and medicinal, pharmacokinetic and computational aspects. | ||
| 650 | 0 | |a Drug development. | |
| 650 | 0 | |a Oxazoles. | |
| 650 | 2 | |a Oxazoles |0 (DNLM)D010080 | |
| 650 | 6 | |a Médicaments |x Développement. |0 (CaQQLa)201-0306620 | |
| 650 | 6 | |a Oxazoles. |0 (CaQQLa)201-0093793 | |
| 650 | 7 | |a Drug development |2 fast |0 (OCoLC)fst00898670 | |
| 650 | 7 | |a Oxazoles |2 fast |0 (OCoLC)fst01049536 | |
| 700 | 1 | |a Ghani, Ambreen, |e author. | |
| 700 | 1 | |a Sadiq, Zubi, |e author. | |
| 776 | 0 | 8 | |i Print version: |a Hussain, Erum Akbar |t Oxazole, Isoxazole, Benzoxazole-Based Drug Discovery |d San Diego : Elsevier,c2024 |z 9780323853866 |
| 856 | 4 | 0 | |3 ScienceDirect |u https://www.sciencedirect.com/science/book/9780323853866 |