Polymers for oral drug delivery technologies /

Polymers for Oral Drug Delivery Technologies covers the fundamentals of oral drug delivery and various aspects of polymer technology in oral drug delivery, from classification and synthesis, to applications and regulatory factors. It presents the oral delivery?of therapeutics for treating a number o...

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שמור ב:
מידע ביבליוגרפי
מחברים אחרים: Parambath, Anilkumar
פורמט: אלקטרוני ספר אלקטרוני
שפה:אנגלית
יצא לאור: Cambridge, MA : Woodhead Publishing, [2025]
סדרה:Woodhead Publishing Series in Biomaterials
נושאים:
גישה מקוונת:ScienceDirect
תגים: הוספת תג
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040 |a OPELS  |b eng  |e rda  |e pn  |c OPELS  |d OCLCO  |d OCLCL  |d SFB  |d OCLCF  |d OCLCO 
020 |z 9780443137747 
035 |a (OCoLC)1460738008 
050 4 |a RS199.5 
082 0 4 |a 615/.6  |2 23/eng/20241014  |1 https://id.oclc.org/worldcat/ddc/E3TwF968xWhtc3dQv3rxRjX3dJ 
245 0 0 |a Polymers for oral drug delivery technologies /  |c edited by Anilkumar Parambath. 
264 1 |a Cambridge, MA :  |b Woodhead Publishing,  |c [2025] 
300 |a 1 online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 0 |a Woodhead Publishing Series in Biomaterials 
520 |a Polymers for Oral Drug Delivery Technologies covers the fundamentals of oral drug delivery and various aspects of polymer technology in oral drug delivery, from classification and synthesis, to applications and regulatory factors. It presents the oral delivery?of therapeutics for treating a number of diseases, along with the challenges of oral drug administration to assure a predictive and reproducible pharmacokinetic profile of active pharmaceutical ingredients (API). Polymers play an important role to achieve the targeted release profile consistently of an API in vivo by various functionalities like drug protection from gastric juice, fast release and supersaturation or release within a targeted area of the GI tract. 
500 |a Includes index. 
588 0 |a Online resource; title from PDF title page (ScienceDirect, viewed October 14, 2024). 
505 8 |a Front Cover -- Polymers for Oral Drug Delivery Technologies -- Copyright Page -- Contents -- List of contributors -- Preface -- I. Fundamentals of oral drug delivery -- 1 Gastrointestinal tract environment and its implications on oral drug delivery -- 1.1 Introduction -- 1.2 Overview of the gastrointestinal tract -- 1.3 Key regions of the gastrointestinal tract involved in oral drug delivery and absorption: physiological differences and ... -- 1.3.1 The oral cavity: gateway to the gastrointestinal tract -- 1.3.1.1 Saliva composition and its role in oral drug delivery -- 1.3.1.2 Enzymes in saliva: amylase and its impact on drug delivery -- 1.3.1.3 Other enzymes found in saliva -- 1.3.1.4 pH variations in the oral cavity and their influence on drug absorption -- 1.3.2 Stomach: unraveling its crucial role in drug absorption -- 1.3.2.1 Gastric juice composition and its impact on drug absorption -- Hydrochloric acid -- Pepsin and proteases -- 1.3.2.2 pH variations in the stomach and their implications for drug delivery -- 1.3.3 Intestinal interplay: deciphering the dynamics of drug absorption in small intestine -- 1.3.3.1 Bile salts and their role in absorption -- 1.3.3.2 Enzymatic environment in the small intestine -- Pancreatic enzymes and their role in drug digestion and absorption -- Brush border enzymes and their impact on drug metabolism -- 1.3.3.3 pH variations in the small intestine -- Impact of pH on drug solubility -- Importance of pH and pKa determination -- Henderson-Hasselbalch equation  |7 Generated by AI 
650 0 |a Drug delivery systems. 
650 0 |a Polymers in medicine. 
650 2 |a Drug Delivery Systems  |0 (DNLM)D016503 
650 6 |a Systèmes d'administration de médicaments.  |0 (CaQQLa)000260397 
650 6 |a Polymères en médecine.  |0 (CaQQLa)201-0024435 
650 7 |a Drug delivery systems  |2 fast  |0 (OCoLC)fst00898667 
650 7 |a Polymers in medicine  |2 fast  |0 (OCoLC)fst01070661 
700 1 |a Parambath, Anilkumar. 
856 4 0 |3 ScienceDirect  |u https://www.sciencedirect.com/science/book/9780443137747