Molecular pathway analysis using high-throughput OMICS molecular data : analysis of molecular pathway composition, architecture, and activation using high-throughput genomic, epigenetic, transcriptomic, proteomic, and metabolomic data /
The field of molecular pathway analysis evolves rapidly, and many progressive methods have recently been discovered. This book contains the largest collections of molecular pathways. For the first time, guidelines on how to do genomic, epigenetic, transcriptomic, proteomic, and metabolomic data anal...
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| Médium: | Elektronický zdroj E-kniha |
| Jazyk: | angličtina |
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London, U.K. ; San Diego, CA :
Academic Press,
[2025]
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| On-line přístup: | ScienceDirect |
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| 245 | 0 | 0 | |a Molecular pathway analysis using high-throughput OMICS molecular data : |b analysis of molecular pathway composition, architecture, and activation using high-throughput genomic, epigenetic, transcriptomic, proteomic, and metabolomic data / |c edited by Anton Buzdin. |
| 264 | 1 | |a London, U.K. ; |a San Diego, CA : |b Academic Press, |c [2025] | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 520 | |a The field of molecular pathway analysis evolves rapidly, and many progressive methods have recently been discovered. This book contains the largest collections of molecular pathways. For the first time, guidelines on how to do genomic, epigenetic, transcriptomic, proteomic, and metabolomic data analysis in real-world research practice are given. It also focuses on the pathway analysis applications for solving tasks in biotechnology, pharmaceutics, and molecular diagnostics. It demonstrates how pathway analysis can be applied for the research and treatment of chronic and acute diseases, for next-generation molecular diagnostics, for drug design and preclinical testing; relevant real-world examples, molecular tests, and web resources will be reviewed in-depth. The book shows a tendency of erasing the borders between chemistry, physics, informatics, mathematics, biology, and medicine by means of novel research approaches and instruments, providing a truly multidisciplinary approach. | ||
| 532 | 1 | |3 EBSCOhost |a "EBSCO evaluates our products based on the Web Content Accessibility Guidelines (WCAG) and the related Section 508 and EN 301 549 regulations in the US and EU. Most EBSCO products are substantially conformant with WCAG 2.2 level AA." Source: https://connect.ebsco.com/s/article/EBSCO-VPATs?language=en_US. Last accessed April 22, 2025. | |
| 588 | |a Description based on online resource; title from digital title page (viewed on June 13, 2025). | ||
| 505 | 8 | |a Front Cover -- Molecular Pathway Analysis Using High-Throughput OMICS Molecular Data -- Molecular Pathway Analysis Using High-Throughput OMICS Molecular Data -- Copyright -- Dedication -- Contents -- Contributors -- About the editor -- Preface -- I -Foundational information -- 1 -- Past, current, and future of molecular pathway analysis -- 1.1 Molecular pathways -- 1.2 Quantitative omics data -- 1.3 Different levels of omics data analysis -- 1.4 Quantization of IMP activities -- 1.4.1 Annotation of functional roles for pathway participants -- 1.5 Applications of IMP analysis -- 1.5.1 Applications in medicine -- 1.6 Software for quantitative assessment of IMP activation -- 1.7 Concluding remarks -- References -- 2 -- Molecular data for the pathway analysis -- 2.1 Omics data available for the molecular pathway analysis -- 2.2 Data needed to reconstruct IMPs -- 2.3 Data needed to estimate activation levels of IMPs -- References -- 3 -- Benefits and challenges of OMICS data integration at the pathway level -- 3.1 Background -- 3.2 The comparison -- 3.2.1 Functional annotation of gene expression data |7 Generated by AI | |
| 650 | 0 | |a Genomics. | |
| 650 | 0 | |a Molecular biology. | |
| 650 | 0 | |a High-throughput nucleotide sequencing. | |
| 650 | 6 | |a Génomique. |0 (CaQQLa)201-0363181 | |
| 650 | 6 | |a Biologie moléculaire. |0 (CaQQLa)201-0064024 | |
| 650 | 7 | |a molecular biology. |2 aat |0 (CStmoGRI)aat300054470 | |
| 650 | 7 | |a Genomics |2 fast |0 (OCoLC)fst00940228 | |
| 650 | 7 | |a High-throughput nucleotide sequencing |2 fast |0 (OCoLC)fst02060599 | |
| 650 | 7 | |a Molecular biology |2 fast |0 (OCoLC)fst01024734 | |
| 700 | 1 | |a Buzdin, Anton, |e editor. |1 https://id.oclc.org/worldcat/entity/E39PCjBG8yxPwDQGjF9CvyVYKd | |
| 776 | 0 | 8 | |i Print version: |z 0443155682 |z 9780443155680 |w (OCoLC)1391433058 |
| 856 | 4 | 0 | |3 ScienceDirect |u https://www.sciencedirect.com/science/book/9780443155680 |