T cell metabolism and cancer immunotherapy /

Delves into the intricate regulation of T-cell immunity and tolerance. As research advances in cell-based therapies, the potential of engineered immune cells to treat cancers and other diseases is becoming increasingly evident due to their powerful capabilities. Additionally, the book offers valuabl...

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Bibliographische Detailangaben
Weitere Verfasser: Song, Jianxun (Immunologist) (HerausgeberIn)
Format: Elektronisch E-Book
Sprache:Englisch
Veröffentlicht: London, U.K. ; San Diego, CA : Academic Press, [2025]
Schriftenreihe:Breaking tolerance to anti-cancer cell-mediated immunotherapy ; v. 8.
Schlagworte:
Online-Zugang:ScienceDirect
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020 |z 9780443138270  |q (print) 
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050 4 |a QR185.8.T2 
082 0 4 |a 616.07/97  |2 23/eng/20241210  |1 https://id.oclc.org/worldcat/ddc/E3wvhrcdCGHY3qQ6KqWDYVgcBF 
245 0 0 |a T cell metabolism and cancer immunotherapy /  |c edited by Jianxun Song, Department of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan, TX, United States. 
264 1 |a London, U.K. ;  |a San Diego, CA :  |b Academic Press,  |c [2025] 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Breaking tolerance to anti-cancer cell-mediated immunotherapy ;  |v volume 8 
504 |a Includes bibliographical references and index. 
505 0 |a Modulating T cell metabolism to improve T cell therapy / Yating Li, Shao-Hsi Hung, Cassian Yee -- Links between the DNA damage response and immune response in cancer / Agnes Malysa, Jianxun Jim Song, Xiaohong Mary Zhang -- Improving adoptive T cell therapy by positive conversion of negative signaling / Jin-Qing Liu, Bolin Zhao, Xue-Feng Bai -- TGF-ß in tumor microenvironment, metabolism, and immunotherapy / Haotian Bai, Yisong Y. Wan -- Targeting immunometabolism to improve cancer therapies / Darby J. Ballard, Liqing Wang, Jianxun Song -- TCR-T cells for cancer immunotherapy / Mohamed Shawky Hussein, Rui Mao, Yukai He -- The combination of local treatment and immunotherapy / Bo Zhu, Jianguo Sun, Shimeng Liang -- T cell metabolism and cancer immunotherapy / Qianqian Li, Zhuangzhuang Zhang -- Exploring the interplay of kinases and transcription factors in immunometabolism / Darby J. Ballard, Liqing Wang, Jianxun Song -- Targeting engineered bacteria to improve cancer immunotherapy / Aiswarya Dash, Sonakshi Bahuguna, Jugal Kishore Das -- Salmonella: A bacterial warrior in cancer immunotherapy / Wei Kong, Lingchen Fu, Yixin Shi -- Oncolytic virus for cancer immunotherapy / Penghui Yang, Hao Yang -- Advances in immunotherapy for colorectal cancer / Shuai Lu, Benqiang Rao, Penghui Yang. 
520 |a Delves into the intricate regulation of T-cell immunity and tolerance. As research advances in cell-based therapies, the potential of engineered immune cells to treat cancers and other diseases is becoming increasingly evident due to their powerful capabilities. Additionally, the book offers valuable insights into developing and optimizing strategies for bacterium-based immunotherapies. Despite great advancement in immunotherapy such as adoptive T cell transfer-based regimen, the clinical outcomes remain less satisfactory due to a variety of factors that lessen its therapeutic efficacy. By determining the role and importance of T cell metabolism in the regulation of T lymphocytes that are related to the development and managements of aberrant immunity, T Cell Metabolism and Cancer Immunotherapy designs and develops novel and more effective strategies for improving regimens for patients with aberrant immunity. Within ten chapters the content not only reveals targets of T cell metabolism as critical determinants of immune regulation, but also uncovers unique therapeutic opportunities to improve immunotherapy through targeting T cell metabolism. This fills a significant gap in the knowledge of scientists working in the field of onco-immunology/immunotherapy, and students learning about T cells, metabolism, immunomodulation, and immunotherapy. 
650 0 |a T cells  |x Metabolism. 
650 0 |a Cancer  |x Immunotherapy. 
650 6 |a Cancer  |x Immunothérapie.  |0 (CaQQLa)201-0168739 
650 7 |a Cancer  |x Immunotherapy  |2 fast  |0 (OCoLC)fst00845386 
700 1 |a Song, Jianxun  |c (Immunologist),  |e editor. 
776 0 8 |c Original  |z 0443138273  |z 9780443138270  |w (OCoLC)1391434402 
830 0 |a Breaking tolerance to anti-cancer cell-mediated immunotherapy ;  |v v. 8. 
856 4 0 |3 ScienceDirect  |u https://www.sciencedirect.com/science/book/9780443138270